Page last updated: 2024-08-23

swainsonine and Neoplasms

swainsonine has been researched along with Neoplasms in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (61.54)18.2507
2000's0 (0.00)29.6817
2010's5 (38.46)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, X; Gong, Y; Jiang, J; Li, Y; Liang, Z; Liu, W; Shi, D; Wei, Y; Xing, Y; Yang, F; Zhuang, J1
An, L; Cheng, GC; Li, WW1
Gerber-Lemaire, S; Juillerat-Jeanneret, L1
Gaikwad, SM; Kumar, A1
Beheshti Zavareh, R; Dennis, JW; Gronda, M; Hurren, R; Ketela, T; Maclean, N; Moffat, J; Rose, DR; Schachter, H; Schimmer, AD; Simpson, CD; Sukhai, MA; Swallow, CJ; Wang, X; Zih, F1
Baker, M; Baptista, JA; Dennis, JW; Goss, P; Krepinsky, JJ; Nghiem, M1
Baker, M; Baptiste, J; Dennis, JW; Fernandes, B; Goss, PE1
Das, PC; Olden, K; Roberts, JD; White, SL1
Dhume, ST; George, MD; Klein, JL; Olden, K; Palmantier, R; Roberts, JD1
Bailey, D; Dennis, JW; Goss, PE; Reid, CL1
Breton, P; Gause, BL; Grzegorzewski, K; Newton, SA; Olden, K; Oredipe, OA; White, SL; Yasuda, Y1
Dennis, JW1
Skolnick, A1

Reviews

2 review(s) available for swainsonine and Neoplasms

ArticleYear
The potential importance of swainsonine in therapy for cancers and immunology.
    Pharmacology & therapeutics, 1991, Volume: 50, Issue:3

    Topics: Animals; Bone Marrow; Cell Division; Humans; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Swainsonine

1991
N-linked oligosaccharide processing and tumor cell biology.
    Seminars in cancer biology, 1991, Volume: 2, Issue:6

    Topics: Animals; Biomarkers, Tumor; Carbohydrate Sequence; Cell Adhesion; Glycosylation; Humans; Indolizines; Lewis Blood Group Antigens; Mice; Molecular Sequence Data; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Oligosaccharides; Swainsonine

1991

Trials

3 trial(s) available for swainsonine and Neoplasms

ArticleYear
Measuring swainsonine in serum of cancer patients: phase I clinical trial.
    Clinical chemistry, 1994, Volume: 40, Issue:3

    Topics: Acetylation; Chromatography, Gas; Gas Chromatography-Mass Spectrometry; Humans; Infusions, Intravenous; Leukemia; Neoplasms; Swainsonine

1994
A phase I study of swainsonine in patients with advanced malignancies.
    Cancer research, 1994, Mar-15, Volume: 54, Issue:6

    Topics: Adult; Aged; alpha-Mannosidase; Antigens, Surface; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Golgi Apparatus; Humans; Infusions, Intravenous; Lymphocytes; Male; Mannosidases; Middle Aged; Neoplasms; Oligosaccharides; Swainsonine

1994
Phase IB clinical trial of the oligosaccharide processing inhibitor swainsonine in patients with advanced malignancies.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:7

    Topics: Adult; Aged; alpha-Mannosidase; Animals; Antineoplastic Agents, Phytogenic; Aspartate Aminotransferases; Carbohydrate Conformation; Carbohydrate Sequence; Dose-Response Relationship, Drug; Edema; Female; Head and Neck Neoplasms; Humans; Male; Mannosidases; Mice; Middle Aged; Molecular Sequence Data; Neoplasms; Oligosaccharides; Swainsonine

1997

Other Studies

8 other study(ies) available for swainsonine and Neoplasms

ArticleYear
Complex N-glycan promotes CD133 mono-ubiquitination and secretion.
    FEBS letters, 2019, Volume: 593, Issue:7

    Topics: AC133 Antigen; Antigens, Surface; Biomarkers, Tumor; Cell Line, Tumor; DNA-Binding Proteins; Endosomal Sorting Complexes Required for Transport; Endosomes; Gene Expression Regulation, Neoplastic; Glycosylation; Humans; Neoplasm Metastasis; Neoplasms; Neoplastic Stem Cells; Polysaccharides; Swainsonine; Transcription Factors; Ubiquitination

2019
Fyn arrests swainsonine-induced apoptosis in 293T cells via Akt and its phosphorylation.
    Genetics and molecular research : GMR, 2015, May-18, Volume: 14, Issue:2

    Topics: Apoptosis; Astragalus propinquus; bcl-2-Associated X Protein; HEK293 Cells; Humans; Neoplasms; Oncogene Protein v-akt; Phosphorylation; Plant Extracts; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-fyn; Signal Transduction; Swainsonine

2015
Studies toward new anti-cancer strategies based on alpha-mannosidase inhibition.
    Chimia, 2010, Volume: 64, Issue:9

    Topics: alpha-Mannosidase; Antineoplastic Agents, Phytogenic; Cell Proliferation; Glycosylation; Humans; Neoplasms; Swainsonine

2010
Jack bean α-mannosidase (Jbα-man): tolerance to alkali, chelating and reducing agents and energetics of catalysis and inhibition.
    International journal of biological macromolecules, 2011, Dec-01, Volume: 49, Issue:5

    Topics: Alkalies; alpha-Mannosidase; Antineoplastic Agents, Phytogenic; Biocatalysis; Canavalia; Catalytic Domain; Chelating Agents; Chemistry, Pharmaceutical; Disulfides; Enzyme Stability; Humans; Hydrogen-Ion Concentration; Kinetics; Metalloproteins; Neoplasms; Plant Proteins; Protein Subunits; Swainsonine; Temperature; Thermodynamics; Zinc

2011
Suppression of cancer progression by MGAT1 shRNA knockdown.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Animals; Cell Line, Tumor; Cell Membrane; Disease Progression; Enzyme Inhibitors; Female; HeLa Cells; Humans; Male; Mice; N-Acetylglucosaminyltransferases; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms; Phenotype; Polysaccharides; Prostatic Neoplasms; RNA, Small Interfering; Signal Transduction; Swainsonine

2012
Activation of resident tissue-specific macrophages by swainsonine.
    Oncology research, 1995, Volume: 7, Issue:9

    Topics: Adjuvants, Immunologic; Animals; Cell Death; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages; Macrophages, Alveolar; Macrophages, Peritoneal; Mice; Mice, Inbred C3H; Neoplasms; Spleen; Swainsonine; Time Factors

1995
The role of protein glycosylation inhibitors in the prevention of metastasis and therapy of cancer.
    Cancer detection and prevention, 1998, Volume: 22, Issue:5

    Topics: Animals; Antineoplastic Agents, Phytogenic; Arachidonic Acid; Cell Adhesion; Enzyme Inhibitors; Glycoproteins; Glycosylation; Hematopoietic Stem Cells; Humans; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasms; Protein Kinase C; Signal Transduction; Swainsonine; Tumor Cells, Cultured

1998
Molecular biology research offers new weapons against cancer.
    JAMA, 1990, May-02, Volume: 263, Issue:17

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Alkaloids; Animals; Colonic Neoplasms; Humans; Liposomes; Mannosidases; Mice; Neoplasms; Neoplasms, Experimental; Phosphatidylethanolamines; Research; Swainsonine

1990