suxibuzone has been researched along with Arthritis, Rheumatoid in 4 studies
suxibuzone : A pyrazolidine that is phenylbutazone which is substituted by a 3-carboxypropanoylmethyl group at the 4-position. Suxibuzone is a prodrug for phenylbutazone and is commonly used as an anti-inflammatory drug in horses.
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "One hundred and fifty patients with rheumatoid arthritis received suxibuzone (426 mg/day, equivalent to 300 mg of phenylbutazone), a prodrug of phenylbutazone, or phenylbutazone (300 mg/day) in a six-week double-blind comparison study." | 9.05 | A double-blind comparison of phenylbutazone and suxibuzone, a prodrug of phenylbutazone, in rheumatoid arthritis. ( Honma, M; Kageyama, T; Mizushima, Y; Shiokawa, Y, 1983) |
| "One hundred and fifty patients with rheumatoid arthritis received suxibuzone (426 mg/day, equivalent to 300 mg of phenylbutazone), a prodrug of phenylbutazone, or phenylbutazone (300 mg/day) in a six-week double-blind comparison study." | 5.05 | A double-blind comparison of phenylbutazone and suxibuzone, a prodrug of phenylbutazone, in rheumatoid arthritis. ( Honma, M; Kageyama, T; Mizushima, Y; Shiokawa, Y, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mizushima, Y | 3 |
| Shiokawa, Y | 1 |
| Honma, M | 1 |
| Kageyama, T | 1 |
| Goebel, KM | 1 |
| Hahn, E | 1 |
| Hausmann, L | 1 |
| Storck, U | 1 |
| Kaffarnik, H | 1 |
| Neurath, F | 1 |
3 trials available for suxibuzone and Arthritis, Rheumatoid
| Article | Year |
|---|---|
A double-blind comparison of phenylbutazone and suxibuzone, a prodrug of phenylbutazone, in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Fema | 1983 |
Pro-drugs of non-steroidal anti-inflammatory agents.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Gast | 1983 |
[Current aspects of rheumatoid arthritis].
Topics: Administration, Oral; Adult; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; D | 1979 |
1 other study available for suxibuzone and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Basic and clinical studies of prodrugs of nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Biotransformation; Humans; Indome | 1982 |