suramin has been researched along with Wounds, Stab in 1 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Wounds, Stab: Penetrating wounds caused by a pointed object.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Suramin-treated animals showed an obvious reduction in several parameters of CNS inflammation: cellular proliferation, GFAP levels, and tenascin-C immunoreactivity were reduced in suramin-treated as compared to control animals at early time points." | 1.30 | Suramin disrupts the gliotic response following a stab wound injury to the adult rat brain. ( Di Prospero, NA; Geller, HM; Ho, SY; McAuliffe, WG; Meiners, S; Zhou, XR, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Di Prospero, NA | 1 |
| Zhou, XR | 1 |
| Meiners, S | 1 |
| McAuliffe, WG | 1 |
| Ho, SY | 1 |
| Geller, HM | 1 |
1 other study available for suramin and Wounds, Stab
| Article | Year |
|---|---|
Suramin disrupts the gliotic response following a stab wound injury to the adult rat brain.
Topics: Animals; Antineoplastic Agents; Astrocytes; Brain Injuries; Calcium-Binding Proteins; Cell Division; | 1998 |