suramin has been researched along with Viremia in 1 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Viremia: The presence of viruses in the blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We treated 12 patients who had acquired immunodeficiency syndrome and active HTLV-III/LAV viremia with suramin, a potent competitive inhibitor of reverse transcriptase, in six weekly induction doses of 1 g, followed by weekly maintenance doses of 500 mg." | 7.67 | Suramin antiviral therapy in the acquired immunodeficiency syndrome. Clinical, immunological, and virologic results. ( Aguilar, S; Cohen, J; Formenti, SC; Gill, PS; Hawkins, JG; Krailo, M; Levine, AM; Meyer, PR; Parker, J; Rasheed, S, 1986) |
| " We treated 12 patients who had acquired immunodeficiency syndrome and active HTLV-III/LAV viremia with suramin, a potent competitive inhibitor of reverse transcriptase, in six weekly induction doses of 1 g, followed by weekly maintenance doses of 500 mg." | 3.67 | Suramin antiviral therapy in the acquired immunodeficiency syndrome. Clinical, immunological, and virologic results. ( Aguilar, S; Cohen, J; Formenti, SC; Gill, PS; Hawkins, JG; Krailo, M; Levine, AM; Meyer, PR; Parker, J; Rasheed, S, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Levine, AM | 1 |
| Gill, PS | 1 |
| Cohen, J | 1 |
| Hawkins, JG | 1 |
| Formenti, SC | 1 |
| Aguilar, S | 1 |
| Meyer, PR | 1 |
| Krailo, M | 1 |
| Parker, J | 1 |
| Rasheed, S | 1 |
1 other study available for suramin and Viremia
| Article | Year |
|---|---|
Suramin antiviral therapy in the acquired immunodeficiency syndrome. Clinical, immunological, and virologic results.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antibodies, Viral; Cerebrospinal Fluid; Deltaretrovirus; | 1986 |