suramin has been researched along with Urogenital Neoplasms in 2 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Urogenital Neoplasms: Tumors or cancer of the UROGENITAL SYSTEM in either the male or the female.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cheson, BD | 1 |
| Phillips, PH | 1 |
| Pluda, JM | 1 |
| Christian, M | 1 |
| Scher, HI | 1 |
| Heston, WD | 1 |
1 review available for suramin and Urogenital Neoplasms
| Article | Year |
|---|---|
Suramin as an archetypical compound in the development of growth factor antagonists for inhibition of genitourinary tumors.
Topics: Growth Inhibitors; Humans; Male; Prostatic Neoplasms; Suramin; Tumor Cells, Cultured; Urogenital Neo | 1992 |
1 other study available for suramin and Urogenital Neoplasms
| Article | Year |
|---|---|
Clinical trials referral resource. Clinical trials of suramin.
Topics: Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Humans; Leukemia; Lymphoma; Suram | 1995 |