suramin has been researched along with Urinary Bladder, Overactive in 1 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Urinary Bladder, Overactive: Symptom of overactive detrusor muscle of the URINARY BLADDER that contracts with abnormally high frequency and urgency. Overactive bladder is characterized by the frequent feeling of needing to urinate during the day, during the night, or both. URINARY INCONTINENCE may or may not be present.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Contreras-Sanz, A | 1 |
| Krska, L | 1 |
| Balachandran, AA | 1 |
| Curtiss, NL | 1 |
| Khasriya, R | 1 |
| Kelley, S | 1 |
| Strutt, M | 1 |
| Gill, HS | 1 |
| Taylor, KM | 1 |
| Mansfield, KJ | 1 |
| Wu, C | 1 |
| Peppiatt-Wildman, CM | 1 |
| Malone-Lee, J | 1 |
| Duckett, J | 1 |
| Wildman, SS | 1 |
1 other study available for suramin and Urinary Bladder, Overactive
| Article | Year |
|---|---|
Altered urothelial ATP signaling in a major subset of human overactive bladder patients with pyuria.
Topics: Adenosine Triphosphate; Carbenoxolone; Female; Humans; Male; Purinergic P2 Receptor Antagonists; Pyu | 2016 |