suramin has been researched along with Trypanosomiasis in 73 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Trypanosomiasis: Infection with protozoa of the genus TRYPANOSOMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Suramin is a novel hepsin inhibitor that reduces its protumorigenic and prothrombotic effects in colorectal cancer cells." | 8.31 | Suramin, a drug for the treatment of trypanosomiasis, reduces the prothrombotic and metastatic phenotypes of colorectal cancer cells by inhibiting hepsin. ( Carmona-Bayonas, A; Espín, S; García-Molina, F; Lozano, ML; Martínez-Martínez, I; Mulero, V; Nieto, A; Pardo-Sánchez, I; Peña-García, J; Peñas-Martínez, J; Pérez-Sánchez, H; Ricote, G; Rodenas, MC; Vicente, V; Zaragoza-Huesca, D, 2023) |
| "Suramin is a novel hepsin inhibitor that reduces its protumorigenic and prothrombotic effects in colorectal cancer cells." | 4.31 | Suramin, a drug for the treatment of trypanosomiasis, reduces the prothrombotic and metastatic phenotypes of colorectal cancer cells by inhibiting hepsin. ( Carmona-Bayonas, A; Espín, S; García-Molina, F; Lozano, ML; Martínez-Martínez, I; Mulero, V; Nieto, A; Pardo-Sánchez, I; Peña-García, J; Peñas-Martínez, J; Pérez-Sánchez, H; Ricote, G; Rodenas, MC; Vicente, V; Zaragoza-Huesca, D, 2023) |
| " In this study, a new semi-synthetic berberine analogue, 5,6-didehydro-8,8-diethyl-13-oxodihydroberberine chloride (1), showed nanomolar level potency against in vitro models of leishmaniasis, malaria, and trypanosomiasis as well as activity in an in vivo visceral leishmaniasis model." | 3.77 | Potent antiprotozoal activity of a novel semi-synthetic berberine derivative. ( Anklin, C; Bahar, M; Deng, Y; Doskotch, RW; Drew, ME; Gil, RR; He, S; Kinghorn, AD; Navarro-Vázquez, A; Pandharkar, T; Werbovetz, KA; Zhu, X, 2011) |
| "The first reported human case of trypanosomiasis caused by Trypanosoma evansi was treated using suramin." | 3.73 | Treatment and follow-up of the first case of human trypanosomiasis caused by Trypanosoma evansi in India. ( Chaudhari, A; Dani, VS; Jannin, J; Joshi, PP; Powar, RM; Shegokar, VR; Somalwar, AM; Truc, P, 2006) |
| "Suramin is a polysulfonated polyaromatic symmetrical urea." | 2.44 | Suramin: clinical uses and structure-activity relationships. ( Bennett, AJ; Cosgrove, KL; McGeary, RP; Ross, BP; Tran, QB, 2008) |
| "The parasitemia was monitored daily through blood smear, and the treatment of all groups was performed three days post-infection (PI), when all mice showed increased parasitemia." | 1.39 | Susceptibility of Brazilian isolates of Trypanosoma evansi to suramin sodium: test in experimentally infected mice. ( Da Silva, AS; Faccio, L; Gressler, LT; Lazzarotto, CR; Miletti, LC; Monteiro, SG; Tonin, AA, 2013) |
| "Suramin was not effective." | 1.39 | Evaluation of trypanocidal drugs used for human African trypanosomosis against Trypanosoma lewisi. ( Bucheton, B; Courtois, P; Cuny, G; Daulouède, S; Dethoua, M; Nzoumbou-Boko, R; Semballa, S; Truc, P; Vincendeau, P, 2013) |
| " All four bears were treated twice at 3-day intervals with suramin sodium by using almost twice the dosage recommended for common domestic animals (10 mg/kg)." | 1.34 | Trypanosoma evansi infections in Himalayan black bears (Selenarctos thibetanus). ( Muhammad, G; Naureen, A; Sajid, MS; Saqib, M, 2007) |
| " In vivo experiments in mice with selected isolates showed that the isolate most resistant to suramin was not cured at a dosage of 10 mg/kg, while the isolate that was most resistant to antrycide showed only 50% cure rate at a dose rate of 5 mg/kg." | 1.32 | Resistance to drug by different isolates Trypanosoma evansi in China. ( Liao, D; Lin, J; Shen, J; Zhou, J; Zhou, Y, 2004) |
| " It therefore appears that drug bioavailability is altered or drug biotransformation occurs during the in vivo test." | 1.28 | In vivo and in vitro sensitivity of Trypanosoma evansi and T. equiperdum to diminazene, suramin, MelCy, quinapyramine and isometamidium. ( Baltz, T; Giroud, C; Zhang, ZQ, 1991) |
| "Suramin was very effective, even after combined therapy had failed repeatedly, while melarsoprol was less effective." | 1.27 | Trypanosoma brucei and T. vivax: salicylhydroxamic acid and glycerol treatment of acute and chronically infected rats. ( van der Meer, C; Versluijs-Broers, JA, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 48 (65.75) | 18.7374 |
| 1990's | 9 (12.33) | 18.2507 |
| 2000's | 8 (10.96) | 29.6817 |
| 2010's | 7 (9.59) | 24.3611 |
| 2020's | 1 (1.37) | 2.80 |
| Authors | Studies |
|---|---|
| Chauvière, G | 1 |
| Bouteille, B | 1 |
| Enanga, B | 1 |
| de Albuquerque, C | 1 |
| Croft, SL | 1 |
| Dumas, M | 1 |
| Périé, J | 1 |
| Gillingwater, K | 2 |
| Kumar, A | 2 |
| Anbazhagan, M | 1 |
| Boykin, DW | 2 |
| Tidwell, RR | 2 |
| Brun, R | 2 |
| Bahar, M | 1 |
| Deng, Y | 1 |
| Zhu, X | 1 |
| He, S | 1 |
| Pandharkar, T | 1 |
| Drew, ME | 1 |
| Navarro-Vázquez, A | 1 |
| Anklin, C | 1 |
| Gil, RR | 1 |
| Doskotch, RW | 1 |
| Werbovetz, KA | 1 |
| Kinghorn, AD | 1 |
| Zaragoza-Huesca, D | 1 |
| Rodenas, MC | 1 |
| Peñas-Martínez, J | 1 |
| Pardo-Sánchez, I | 1 |
| Peña-García, J | 1 |
| Espín, S | 1 |
| Ricote, G | 1 |
| Nieto, A | 1 |
| García-Molina, F | 1 |
| Vicente, V | 1 |
| Lozano, ML | 1 |
| Carmona-Bayonas, A | 1 |
| Mulero, V | 1 |
| Pérez-Sánchez, H | 1 |
| Martínez-Martínez, I | 1 |
| Faccio, L | 1 |
| Da Silva, AS | 1 |
| Gressler, LT | 1 |
| Tonin, AA | 1 |
| Lazzarotto, CR | 1 |
| Miletti, LC | 1 |
| Monteiro, SG | 1 |
| Dethoua, M | 1 |
| Nzoumbou-Boko, R | 1 |
| Truc, P | 4 |
| Daulouède, S | 1 |
| Courtois, P | 1 |
| Bucheton, B | 1 |
| Cuny, G | 1 |
| Semballa, S | 1 |
| Vincendeau, P | 1 |
| Cnops, J | 1 |
| Bockstal, V | 1 |
| De Trez, C | 1 |
| Miquel, MC | 1 |
| Radwanska, M | 1 |
| Magez, S | 1 |
| Birhanu, H | 1 |
| Gebrehiwot, T | 1 |
| Goddeeris, BM | 1 |
| Büscher, P | 2 |
| Van Reet, N | 1 |
| McGeary, RP | 1 |
| Bennett, AJ | 1 |
| Tran, QB | 1 |
| Cosgrove, KL | 1 |
| Ross, BP | 1 |
| Ismail, MA | 1 |
| Arafa, RK | 1 |
| Stephens, CE | 1 |
| Defontis, M | 1 |
| Richartz, J | 1 |
| Engelmann, N | 1 |
| Bauer, C | 1 |
| Schwierk, VM | 1 |
| Moritz, A | 1 |
| COSAR, C | 1 |
| DUCROT, R | 1 |
| GAILLIOT, P | 1 |
| BAGET, J | 1 |
| KALTENBACH, A | 1 |
| MASSEGUIN, A | 1 |
| CAUSSE, M | 1 |
| RICOSSE, M | 1 |
| WILLIAMSON, J | 6 |
| DESOWITZ, RS | 2 |
| WATSON, HJ | 1 |
| STEPHEN, LE | 4 |
| NEUJEAN, G | 1 |
| SOLTYS, MA | 3 |
| HAWKING, F | 2 |
| SEN, AB | 1 |
| BERG, SS | 1 |
| BROWN, KN | 1 |
| LUCAS, JM | 1 |
| SCHNEIDER, J | 2 |
| CAHILL, KM | 1 |
| GILL, BS | 5 |
| MALHOTRA, MN | 2 |
| ORMEROD, WE | 2 |
| SHAW, JJ | 1 |
| LIMBOS, P | 1 |
| JADIN, J | 1 |
| WALLS, LP | 1 |
| TELLA, A | 1 |
| KILLICK-KENDRICK, R | 1 |
| Zhou, J | 1 |
| Shen, J | 1 |
| Liao, D | 1 |
| Zhou, Y | 1 |
| Lin, J | 1 |
| Joshi, PP | 3 |
| Shegokar, VR | 3 |
| Powar, RM | 3 |
| Herder, S | 1 |
| Katti, R | 1 |
| Salkar, HR | 1 |
| Dani, VS | 3 |
| Bhargava, A | 2 |
| Jannin, J | 3 |
| Wéry, M | 1 |
| Burke, J | 1 |
| Chaudhari, A | 1 |
| Somalwar, AM | 1 |
| Tankhiwale, NS | 1 |
| Muhammad, G | 1 |
| Saqib, M | 1 |
| Sajid, MS | 1 |
| Naureen, A | 1 |
| Abebe, G | 1 |
| Jones, TW | 2 |
| Boid, R | 3 |
| Monzón, CM | 1 |
| Jara, A | 1 |
| Nantulya, VM | 1 |
| Fang, Y | 1 |
| Ye, WX | 1 |
| Nei, HY | 1 |
| Wang, YL | 1 |
| Voogd, TE | 1 |
| Vansterkenburg, EL | 1 |
| Wilting, J | 1 |
| Janssen, LH | 1 |
| Mutugi, MW | 1 |
| Luckins, AG | 3 |
| Le, NM | 1 |
| Wuyts, N | 1 |
| Nguyen, AD | 1 |
| Nguyen, TG | 1 |
| Gray, AR | 1 |
| Rae, P | 1 |
| James, DM | 1 |
| Goodwin, LG | 1 |
| Tierney, ED | 1 |
| Buyst, H | 1 |
| Olowe, SA | 1 |
| Otsyula, M | 1 |
| Kamar, K | 1 |
| Mutugi, M | 1 |
| Njogu, AR | 1 |
| Zhang, ZQ | 1 |
| Giroud, C | 1 |
| Baltz, T | 1 |
| Payne, RC | 2 |
| Sukanto, IP | 1 |
| Graydon, R | 1 |
| Saroso, H | 1 |
| Jusuf, SH | 1 |
| Takada, S | 1 |
| Dieleman, EF | 1 |
| Ali, BH | 1 |
| Hassan, T | 1 |
| Malik, KH | 1 |
| van der Meer, C | 1 |
| Versluijs-Broers, JA | 1 |
| Nickel, P | 1 |
| Haack, HJ | 1 |
| Widjaja, H | 1 |
| Ardanuy, U | 1 |
| Gurgel, C | 1 |
| Düwel, D | 1 |
| Loewe, H | 1 |
| Raether, W | 1 |
| Hill, GC | 1 |
| Hutner, SH | 1 |
| Walker, PJ | 1 |
| Opiyo, EA | 1 |
| Woo, P | 2 |
| Bailey, NM | 1 |
| Boreham, PF | 1 |
| Venkatesan, S | 1 |
5 reviews available for suramin and Trypanosomiasis
| Article | Year |
|---|---|
Suramin: clinical uses and structure-activity relationships.
Topics: Animals; Antineoplastic Agents; Humans; Neoplasms; Onchocerciasis; Structure-Activity Relationship; | 2008 |
THE CHEMOTHERAPY OF TRYPANOSOMIASIS.
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antimony; Antiprotozoal Agents; Arsenic | 1963 |
Recent research on the biological activity of suramin.
Topics: Acquired Immunodeficiency Syndrome; Animals; Filarioidea; Humans; Neoplasms; Onchocerciasis; Recepto | 1993 |
Suramin: with special reference to onchocerciasis.
Topics: Animals; Blood Coagulation; Chemical Phenomena; Chemistry; Filaricides; Humans; Lysosomes; Onchocerc | 1978 |
Trypanosomiasis in Indonesia. A review of research, 1900-1983.
Topics: Animals; Arthropod Vectors; Diminazene; Phenanthridines; Suramin; Trypanosomiasis | 1986 |
1 trial available for suramin and Trypanosomiasis
| Article | Year |
|---|---|
Preliminary efficacy trial of Cymelarsan, a novel trypanocide, in camels naturally infected with Trypanosoma evansi in Kenya.
Topics: Animals; Arsenicals; Camelus; Dose-Response Relationship, Drug; Injections, Subcutaneous; Kenya; Sur | 1992 |
67 other studies available for suramin and Trypanosomiasis
| Article | Year |
|---|---|
Synthesis and biological activity of nitro heterocycles analogous to megazol, a trypanocidal lead.
Topics: Animals; Cell Line; Chlorocebus aethiops; In Vitro Techniques; Leishmania; Macrophages, Peritoneal; | 2003 |
In vivo investigations of selected diamidine compounds against Trypanosoma evansi using a mouse model.
Topics: Animals; Disease Models, Animal; Female; Mice; Parasitic Sensitivity Tests; Pentamidine; Trypanocida | 2009 |
Potent antiprotozoal activity of a novel semi-synthetic berberine derivative.
Topics: Animals; Antiprotozoal Agents; Berberine; Chlorocebus aethiops; Disease Models, Animal; Inhibitory C | 2011 |
Suramin, a drug for the treatment of trypanosomiasis, reduces the prothrombotic and metastatic phenotypes of colorectal cancer cells by inhibiting hepsin.
Topics: Animals; Caco-2 Cells; Colorectal Neoplasms; Humans; Molecular Docking Simulation; Phenotype; Surami | 2023 |
Susceptibility of Brazilian isolates of Trypanosoma evansi to suramin sodium: test in experimentally infected mice.
Topics: Animals; Brazil; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Mice; Parasitemia | 2013 |
Evaluation of trypanocidal drugs used for human African trypanosomosis against Trypanosoma lewisi.
Topics: Animals; Eflornithine; Female; Humans; Immunocompromised Host; Inhibitory Concentration 50; Melarsop | 2013 |
Curative drug treatment of trypanosomosis leads to the restoration of B-cell lymphopoiesis and splenic B-cell compartments.
Topics: Animals; B-Lymphocyte Subsets; Bone Marrow; Diminazene; Female; Lymphopoiesis; Mice; Mice, Inbred C5 | 2015 |
New Trypanosoma evansi Type B Isolates from Ethiopian Dromedary Camels.
Topics: Animals; Arsenicals; Camelus; Diminazene; DNA, Kinetoplast; DNA, Protozoan; Ethiopia; Genotype; Mice | 2016 |
In vitro activity and preliminary toxicity of various diamidine compounds against Trypanosoma evansi.
Topics: Amidines; Animals; Arsenicals; Cells, Cultured; Diminazene; Drug Resistance; Female; Inhibitory Conc | 2010 |
Canine Trypanosoma evansi infection introduced into Germany.
Topics: Amoxicillin-Potassium Clavulanate Combination; Animals; Anti-Bacterial Agents; Anti-Inflammatory Age | 2012 |
[Study of the suramin pentamidine salt].
Topics: Pentamidine; Sodium Chloride; Sodium Chloride, Dietary; Suramin; Trypanosomiasis | 1954 |
[The leukocyte picture in natural and experimental surra infection; results of the Austrian expedition to Iran 1949-50].
Topics: Animals; Expeditions; Iran; Leukocytes; Leukocytosis; Suramin; Trypanosomiasis | 1954 |
[Preliminary note on combined lomidine and moranyl in the prevention of sleeping sickness].
Topics: Amidines; Animals; Biomedical Research; Humans; Pentamidine; Suramin; Trypanosomiasis; Trypanosomias | 1955 |
Prophylactic activity of suramin complexes in animal trypanosomiasis.
Topics: Animals; Cattle; Suramin; Trypanosomiasis | 1956 |
Suramin complexes. I. Prophylactic activity against Trypanosoma congolense in small animals.
Topics: Animals; Suramin; Trypanosoma congolense; Trypanosomiasis; Trypanosomiasis, African | 1957 |
Suramin complexes. II. Prophylactic activity against Trypanosoma vivax in cattle.
Topics: Animals; Cattle; Suramin; Trypanosoma vivax; Trypanosomiasis | 1957 |
Suramin complexes. III. Preliminary experiments on Trypanosoma simiae infections in pigs.
Topics: Animals; Suramin; Swine; Trypanosoma; Trypanosomiasis | 1958 |
Suramin complexes. IV. Ethidium bromide complex: a largescale laboratory trial of its prophylactic activity in cattle.
Topics: Animals; Cattle; Cattle Diseases; Ethidium; Laboratories; Quinolines; Suramin; Trypanosomiasis | 1958 |
Suramin complexes. V. Ethidium complex: attempts to overcome the injection-site reaction in cattle.
Topics: Animals; Black People; Cattle; Cattle Diseases; Ethidium; Humans; Quinolines; Suramin; Trypanosomias | 1958 |
[Chemotherapy and chemoprophylaxis of sleeping sickness caused by Trypanosoma gambiense].
Topics: Animals; Arsenicals; Chemoprevention; Humans; Pentamidine; Suramin; Trypanosoma brucei gambiense; Tr | 1959 |
Immunity in trypanosomiasis. III. Sensitivity of antibody-resistant strains to chemotherapeutic drugs.
Topics: Antibodies; Humans; Immunoglobulins; Quinolines; Suramin; Trypanosomiasis | 1959 |
The trypanocidal action of homidium, quinapyramine and suramin.
Topics: Animals; Arsenicals; Ethidium; Mice; Pentamidine; Quinolines; Quinolinium Compounds; Suramin; Trypan | 1960 |
Suramin complexes. VII. Further attempts to overcome the ethidium complex injection-site reaction.
Topics: Animals; Cattle; Cattle Diseases; Ethidium; Quinolines; Sheep; Sheep Diseases; Suramin; Trypanosomia | 1961 |
The trypanocidal activity and local tolerance of sparingly soluble salts of metamidium.
Topics: Antiparasitic Agents; Salts; Suramin; Trypanosomiasis; Trypanosomiasis, African | 1961 |
Suramin complexes. X. Comparison of the prophylactic activity of prothidium-suramin complex and prothidium bromide in West African Zebu cattle.
Topics: Animals; Black People; Bromides; Cattle; Cattle Diseases; Humans; Phenanthridines; Quinolines; Suram | 1962 |
[Treatment of human African trypanosomiasis].
Topics: Amidines; Animals; Antiparasitic Agents; Humans; Suramin; Trypanosomiasis; Trypanosomiasis, African | 1963 |
Chemotherapy and chemoprophylaxis of African trypanosomiasis.
Topics: Acridines; Amidines; Animals; Anti-Bacterial Agents; Arsenicals; Chemoprevention; Drug Resistance; D | 1962 |
THE HUMAN TRYPANOSOMATIDAE. I.
Topics: Amidines; Animals; Dimercaprol; Humans; Pathology; Suramin; Trypanosomatina; Trypanosomiasis; Trypan | 1963 |
PROPHYLACTIC ACTIVITY OF SURAMIN COMPLEXES IN 'SURRA' (TRYPANOSOMA EVANSI).
Topics: Animals; Antiprotozoal Agents; India; Mice; Pharmacology; Quinolines; Rats; Research; Suramin; Trypa | 1963 |
A STUDY OF GRANULES AND OTHER CHANGES IN PHASE-CONTRAST APPEARANCE PRODUCED BY CHEMOTHERAPEUTIC AGENTS IN TRYPANOSOMES.
Topics: Animals; Antineoplastic Agents; Antiprotozoal Agents; Fluorescence; Histology; Mice; Microscopy; Mic | 1963 |
[STUDY OF A SLIGHTLY VIRULENT STRAIN OF T. GAMBIENSE ISOLATED IN A EUROPEAN IN THE FORMER BELGIAN CONGO].
Topics: Animals; Antiprotozoal Agents; Carrier State; Cerebrospinal Fluid; Congo; Democratic Republic of the | 1963 |
CHEMOTHERAPY OF TROPICAL DISEASES.
Topics: Amebiasis; Amebicides; Anti-Bacterial Agents; Antimalarials; Antimony; Arsenicals; Chagas Disease; C | 1964 |
[SLEEPING SICKNESS. AFRICAN TRYPANOSOMIASIS].
Topics: Africa; Africa, Central; Amidines; Animals; Diagnosis; Drug Therapy; Humans; Suramin; Trypanosomiasi | 1964 |
THE APPARENT LOSS OF THE KINETOPLAST OF TRYPANOSOMA EVANSI AFTER TREATMENT OF AN EXPERIMENTALLY INFECTED HORSE WITH BERENIL.
Topics: Amidines; Animals; Blood; Blood Proteins; Cell Nucleus; Diminazene; Erythrocytes; Hemoglobins; Horse | 1964 |
Resistance to drug by different isolates Trypanosoma evansi in China.
Topics: Animals; China; Disease Models, Animal; Drug Resistance; Female; Humans; Male; Mice; Parasitic Sensi | 2004 |
Human trypanosomiasis caused by Trypanosoma evansi in India: the first case report.
Topics: Animals; Humans; India; Male; Middle Aged; Suramin; Trypanocidal Agents; Trypanosoma; Trypanosomiasi | 2005 |
Chemotherapy of human trypanosomiases.
Topics: Arsanilic Acid; Arsenicals; Humans; Suramin; Trypanocidal Agents; Trypanosomiasis | 1989 |
Treatment and follow-up of the first case of human trypanosomiasis caused by Trypanosoma evansi in India.
Topics: Follow-Up Studies; Humans; India; Male; Suramin; Trypanocidal Agents; Trypanosomiasis | 2006 |
A rare case of human trypanosomiasis caused by Trypanosoma evansi.
Topics: Animals; DNA, Protozoan; Humans; India; Male; Middle Aged; Polymerase Chain Reaction; Suramin; Trypa | 2006 |
Trypanosoma evansi infections in Himalayan black bears (Selenarctos thibetanus).
Topics: Animals; Conservation of Natural Resources; Male; Suramin; Treatment Outcome; Trypanocidal Agents; T | 2007 |
Suramin sensitivity of stocks of Trypanosoma evansi isolated in the Sudan.
Topics: Animals; Drug Resistance; Mice; Species Specificity; Sudan; Suramin; Trypanosoma; Trypanosomiasis | 1983 |
Sensitivity of antigen ELISA test for detecting Trypanosoma evansi antigen in horses in the subtropical area of Argentina.
Topics: Animals; Antigens, Protozoan; Argentina; Diminazene; Disease Outbreaks; Enzyme-Linked Immunosorbent | 1995 |
In vitro development of suramin-resistant clones of Trypanosoma evansi.
Topics: Animals; Dose-Response Relationship, Drug; Drug Resistance; Female; Immunosuppression Therapy; Male; | 1994 |
Differences in cloning and sub-cloning success rates in four stocks of Trypanosoma evansi and variation in suramin resistance of the clones.
Topics: Animals; Camelus; Drug Evaluation, Preclinical; Male; Mice; Species Specificity; Suramin; Trypanocid | 1995 |
Drug sensitivity of Trypanosoma evansi and the use of immunoassays in diagnosing infections with T. evansi in buffaloes in Vietnam.
Topics: Agglutination Tests; Animals; Antibodies, Protozoan; Buffaloes; Drug Evaluation, Preclinical; Enzyme | 1998 |
Comparison of the diagnostic value of serum immunoglobulin levels, an enzyme-linked immunosorbent assay and a fluorescent antibody test in experimental infections with Trypanosoma evansi in rabbits.
Topics: Animals; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Immunoglobulin G; Immuno | 1978 |
Prophylactic activity in rodents of trypanocides complexed with dextran.
Topics: Animals; Benzamidines; Dextrans; Diminazene; Dose-Response Relationship, Drug; Drug Combinations; Mi | 1978 |
Trypanocidal activity of blood and tissue fluid from normal and infected rabbits treated with curative drugs.
Topics: Animals; Benzamidines; Body Fluids; Diminazene; Ethidium; Male; Melarsoprol; Mice; Phenanthridines; | 1977 |
Letter: The treatment of congenital trypanosomiasis.
Topics: Humans; Infant, Newborn; Male; Suramin; Trypanosomiasis | 1976 |
A case of congenital trypanosomiasis in Lagos.
Topics: Acid-Base Equilibrium; Autopsy; Brain; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; M | 1975 |
In vivo and in vitro sensitivity of Trypanosoma evansi and T. equiperdum to diminazene, suramin, MelCy, quinapyramine and isometamidium.
Topics: Animals; Arsenicals; Diminazene; Female; Mice; Phenanthridines; Quinolinium Compounds; Suramin; Tryp | 1991 |
An outbreak of trypanosomiasis caused by Trypanosoma evansi on the island of Madura, Indonesia.
Topics: Animals; Antibodies, Protozoan; Buffaloes; Cattle; Disease Outbreaks; Hematocrit; Horse Diseases; Ho | 1990 |
[Drugs used against protozoan infections in man].
Topics: Amebiasis; Aminoquinolines; Antiprotozoal Agents; Humans; Malaria; Metronidazole; Pneumonia, Pneumoc | 1990 |
Malic enzyme type VII isoenzyme as an indicator of suramin resistance in Trypanosoma evansi.
Topics: Animals; Drug Resistance; Egypt; Female; Indonesia; Isoenzymes; Malate Dehydrogenase; Mice; Sudan; S | 1989 |
The efficacy of furazolidone against experimental infections with Trypanosoma evansi in camels and mice in Sudan: comparisons with quinapyramine and suramin.
Topics: Animals; Camelus; Female; Furazolidone; Male; Mice; Quinolinium Compounds; Sudan; Suramin; Trypanoci | 1986 |
Trypanosoma brucei and T. vivax: salicylhydroxamic acid and glycerol treatment of acute and chronically infected rats.
Topics: Animals; Brain; Drug Administration Schedule; Drug Therapy, Combination; Female; Glycerol; Melarsopr | 1986 |
[Potential filaricides. Suramin analogs].
Topics: Animals; Anthelmintics; Chemical Phenomena; Chemistry; Female; Filariasis; Filaricides; Male; Mice; | 1986 |
Effect of trypanocidal drugs on terminal respiration of Crithidia fasciculata.
Topics: Acridines; Amidines; Amobarbital; Antimycin A; Antiprotozoal Agents; Arsenicals; Electron Transport; | 1968 |
The effect of the parasite burden on the curative dose in experimental trypanosomiasis.
Topics: Animals; Arsenicals; Mice; Parasite Egg Count; Suramin; Triazines; Trypanocidal Agents; Trypanosoma | 1973 |
Stimulation of antibodies in Trypanosoma evansi infection of rabbits and their disappearance after treatment of the infection.
Topics: Agglutination Tests; Animals; Antibodies; Complement Fixation Tests; Hemagglutination Tests; Immunod | 1970 |
Studies on the chemoprophylaxis against surra (Trypanosoma evansi).
Topics: Acetates; Amidines; Anilides; Animals; Arsenicals; Azo Compounds; Glycine; Horse Diseases; Horses; I | 1972 |
The effect of suramin on blood and tissue forms of Trypanosoma brucei and Trypanosoma rhodesiense.
Topics: Animals; Liver; Malaria; Mice; Rabbits; Recurrence; Spleen; Suramin; Time Factors; Trypanosoma; Tryp | 1971 |
Drug-resistance in Trypanosoma evansi.
Topics: Amidines; Animals; Drug Resistance, Microbial; Horse Diseases; Horses; Pyrimidines; Quinolinium Comp | 1971 |
Chemoprophylaxis of Trypanosoma evansi infections in ponies.
Topics: Animals; Blood; Female; Horse Diseases; Horses; Injections, Intravenous; Injections, Subcutaneous; M | 1971 |
The number of Trypanosoma rhodesiense required to establish an infection in man.
Topics: Amidines; Benzoates; Body Temperature; Humans; Suramin; Trypanosoma; Trypanosomiasis | 1969 |
Soluble protein and drug resistance.
Topics: Animals; Antibody Formation; Antigens; Drug Resistance, Microbial; Molecular Weight; Proteins; Quino | 1970 |
Biological differences of two substrains of Trypanosoma brucei maintained by syringe passage in two different hosts.
Topics: Animals; Chick Embryo; Guinea Pigs; Humans; Immune Sera; Mice; Species Specificity; Suramin; Trypano | 1970 |