suramin has been researched along with Trypanosomiasis, Bovine in 4 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Trypanosomiasis, Bovine: Infection in cattle caused by various species of trypanosomes.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Payne, RC | 3 |
| Sukanto, IP | 3 |
| Partoutomo, S | 2 |
| Jones, TW | 2 |
| Sitepu, P | 1 |
| Williamson, J | 1 |
| Graydon, R | 1 |
| Saroso, H | 1 |
| Jusuf, SH | 1 |
1 review available for suramin and Trypanosomiasis, Bovine
| Article | Year |
|---|---|
Chemotherapy of African trypanosomiasis.
Topics: Adult; Amidines; Animals; Cattle; Drug Resistance; Drug Therapy, Combination; Humans; Melarsoprol; P | 1976 |
3 other studies available for suramin and Trypanosomiasis, Bovine
| Article | Year |
|---|---|
Efficacy of Cymelarsan treatment of suramin resistant Trypanosoma evansi in cattle.
Topics: Animals; Arsenicals; Cattle; Drug Resistance; Injections, Subcutaneous; Recurrence; Suramin; Treatme | 1994 |
Effect of suramin treatment on the productivity of feedlot cattle in a Trypanosoma evansi endemic area of Indonesia.
Topics: Animals; Body Weight; Cattle; Indonesia; Injections, Intravenous; Suramin; Trypanosomiasis, Bovine | 1994 |
An outbreak of trypanosomiasis caused by Trypanosoma evansi on the island of Madura, Indonesia.
Topics: Animals; Antibodies, Protozoan; Buffaloes; Cattle; Disease Outbreaks; Hematocrit; Horse Diseases; Ho | 1990 |