suramin has been researched along with Sprains and Strains in 1 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Sprains and Strains: A collective term for muscle and ligament injuries without dislocation or fracture. A sprain is a joint injury in which some of the fibers of a supporting ligament are ruptured but the continuity of the ligament remains intact. A strain is an overstretching or overexertion of some part of the musculature.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Muscle healing often is hindered by scar tissue formation after injury." | 1.33 | The use of suramin, an antifibrotic agent, to improve muscle recovery after strain injury. ( Chan, YS; Foster, W; Fu, FH; Huard, J; Li, Y, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chan, YS | 1 |
| Li, Y | 1 |
| Foster, W | 1 |
| Fu, FH | 1 |
| Huard, J | 1 |
1 other study available for suramin and Sprains and Strains
| Article | Year |
|---|---|
The use of suramin, an antifibrotic agent, to improve muscle recovery after strain injury.
Topics: Animals; Antineoplastic Agents; Cicatrix; Fibroblasts; Mice; Mice, Inbred C57BL; Muscle, Skeletal; S | 2005 |