suramin has been researched along with Rida in 1 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Excerpt | Relevance | Reference |
---|---|---|
"This study suggests that treatment of scrapie and related spongiform encephalopathies of animals and man is possible only before the agent has reached the clinical target areas of the brain." | 1.28 | Sulphate polyanions prolong the incubation period of scrapie-infected hamsters. ( Casaccia, P; Cibati, M; Ingrosso, L; Ladogana, A; Masullo, C; Pocchiari, M; Salvatore, M; Xi, YG, 1992) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (100.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Ladogana, A | 1 |
Casaccia, P | 1 |
Ingrosso, L | 1 |
Cibati, M | 1 |
Salvatore, M | 1 |
Xi, YG | 1 |
Masullo, C | 1 |
Pocchiari, M | 1 |
1 other study available for suramin and Rida
Article | Year |
---|---|
Sulphate polyanions prolong the incubation period of scrapie-infected hamsters.
Topics: Animals; Cricetinae; Dextran Sulfate; Dose-Response Relationship, Drug; Mesocricetus; Pentosan Sulfu | 1992 |