Page last updated: 2024-11-04

suramin and Retinitis

suramin has been researched along with Retinitis in 1 studies

Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.

Retinitis: Inflammation of the RETINA. It is rarely limited to the retina, but is commonly associated with diseases of the choroid (CHORIORETINITIS) and of the OPTIC DISK (neuroretinitis).

Research Excerpts

ExcerptRelevanceReference
"Suramin treatment was most effective in suppressing EAU when started concurrently with immunization (afferent)."5.29Suramin treatment suppresses induction of experimental autoimmune uveoretinitis (EAU) in rodents. ( Caspi, RR; Chan, CC; Sartani, G; Silver, PB; Strassmann, G, 1995)
"Suramin treatment was most effective in suppressing EAU when started concurrently with immunization (afferent)."1.29Suramin treatment suppresses induction of experimental autoimmune uveoretinitis (EAU) in rodents. ( Caspi, RR; Chan, CC; Sartani, G; Silver, PB; Strassmann, G, 1995)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sartani, G1
Silver, PB1
Strassmann, G1
Chan, CC1
Caspi, RR1

Other Studies

1 other study available for suramin and Retinitis

ArticleYear
Suramin treatment suppresses induction of experimental autoimmune uveoretinitis (EAU) in rodents.
    Current eye research, 1995, Volume: 14, Issue:10

    Topics: Animals; Autoimmune Diseases; Eye Proteins; Female; Hypersensitivity, Delayed; Immunization; Immunog

1995