suramin has been researched along with Retinal Neovascularization in 1 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Retinal Neovascularization: Formation of new blood vessels originating from the retinal veins and extending along the inner (vitreal) surface of the retina.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The effect of the P2 antagonists, suramin and PPADS, on the extent of oxygen-induced retinal neovascularization was analyzed." | 3.74 | Involvement of purinergic P2 receptors in experimental retinal neovascularization. ( Croxatto, JO; Gallo, JE; Kvanta, A; Mancini, J; Sarman, S; van der Ploeg, I, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sarman, S | 1 |
| Mancini, J | 1 |
| van der Ploeg, I | 1 |
| Croxatto, JO | 1 |
| Kvanta, A | 1 |
| Gallo, JE | 1 |
1 other study available for suramin and Retinal Neovascularization
| Article | Year |
|---|---|
Involvement of purinergic P2 receptors in experimental retinal neovascularization.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Fluorescent Antibody Technique, Indirect; Mice; M | 2008 |