suramin has been researched along with Reperfusion Injury in 3 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Suramin-treated animals had a significant reduction in apoptotic tubular cells and infiltrating leukocytes." | 5.35 | Suramin promotes recovery from renal ischemia/reperfusion injury in mice. ( Chavin, KD; Daubert, RA; Lu, B; Schnellmann, RG; Wang, L; Zhuang, S, 2009) |
| "Suramin-treated animals had a significant reduction in apoptotic tubular cells and infiltrating leukocytes." | 1.35 | Suramin promotes recovery from renal ischemia/reperfusion injury in mice. ( Chavin, KD; Daubert, RA; Lu, B; Schnellmann, RG; Wang, L; Zhuang, S, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhuang, S | 1 |
| Lu, B | 1 |
| Daubert, RA | 1 |
| Chavin, KD | 1 |
| Wang, L | 1 |
| Schnellmann, RG | 1 |
| Ben-Ari, Z | 1 |
| Pappo, O | 1 |
| Yitzhaki, S | 1 |
| Cheporko, Y | 1 |
| Shainberg, A | 1 |
| Zinman, T | 1 |
| Ravid, A | 1 |
| Zemel, R | 1 |
| Bachmatov, L | 1 |
| Kurtzwald, E | 1 |
| Mor, E | 1 |
| Hochhauser, E | 1 |
| Pessina, F | 1 |
| Matteucci, G | 1 |
| Esposito, L | 1 |
| Gorelli, B | 1 |
| Valoti, M | 1 |
| Sgaragli, G | 1 |
3 other studies available for suramin and Reperfusion Injury
| Article | Year |
|---|---|
Suramin promotes recovery from renal ischemia/reperfusion injury in mice.
Topics: Animals; Apoptosis; Blood Urea Nitrogen; Caspase 3; Cell Proliferation; Cells, Cultured; Chemotaxis, | 2009 |
Uridine-5'-triphosphate protects against hepatic- ischemic/reperfusion injury in mice.
Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Blood Pressure; Caspase 3; Ce | 2009 |
Protection of intrinsic nerves of guinea-pig detrusor strips against anoxia/glucopenia and reperfusion injury by taurine.
Topics: Aminoethylphosphonic Acid; Animals; Atropine; Electric Stimulation; Evoked Potentials; Glucose; Guin | 2000 |