suramin has been researched along with Red-Cell Aplasia, Pure in 1 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Red-Cell Aplasia, Pure: Suppression of erythropoiesis with little or no abnormality of leukocyte or platelet production.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (100.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Abkowitz, JL | 1 |
1 other study available for suramin and Red-Cell Aplasia, Pure
Article | Year |
---|---|
Retrovirus-induced feline pure red blood cell aplasia: pathogenesis and response to suramin.
Topics: Amino Acid Sequence; Animals; Bone Marrow; Cats; Colony-Forming Units Assay; Erythrocytes; Hematopoi | 1991 |