Page last updated: 2024-11-04

suramin and Palsy

suramin has been researched along with Palsy in 2 studies

Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.

Research Excerpts

ExcerptRelevanceReference
"Pretreatment with suramin (0."1.30Suramin inhibits the toxic effects of presynaptic neurotoxins at the mouse motor nerve terminals. ( Lin, MJ; Lin-Shiau, SY, 1999)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
de Oliveira, M1
Cavalcante, WL1
Arruda, EZ1
Melo, PA1
Dal-Pai Silva, M1
Gallacci, M1
Lin-Shiau, SY1
Lin, MJ1

Other Studies

2 other studies available for suramin and Palsy

ArticleYear
Antagonism of myotoxic and paralyzing activities of bothropstoxin-I by suramin.
    Toxicon : official journal of the International Society on Toxinology, 2003, Sep-15, Volume: 42, Issue:4

    Topics: Animals; Antivenins; Crotalid Venoms; Drug Antagonism; In Vitro Techniques; Male; Mice; Muscle, Skel

2003
Suramin inhibits the toxic effects of presynaptic neurotoxins at the mouse motor nerve terminals.
    European journal of pharmacology, 1999, Oct-08, Volume: 382, Issue:2

    Topics: Animals; Bungarotoxins; Diaphragm; Evoked Potentials; In Vitro Techniques; Membrane Potentials; Mice

1999