suramin has been researched along with Orchitis in 1 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Orchitis: Inflammation of a TESTIS. It has many features of EPIDIDYMITIS, such as swollen SCROTUM; PAIN; PYURIA; and FEVER. It is usually related to infections in the URINARY TRACT, which likely spread to the EPIDIDYMIS and then the TESTIS through either the VAS DEFERENS or the lymphatics of the SPERMATIC CORD.
| Excerpt | Relevance | Reference |
|---|---|---|
| "African trypanosomiasis is a re-emerging disease." | 1.33 | Orchitis as an unusual manifestation of human African trypanosomiasis. ( Burchard, GD; Ehrhardt, S; Lippert, U; Sudeck, H, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ehrhardt, S | 1 |
| Lippert, U | 1 |
| Burchard, GD | 1 |
| Sudeck, H | 1 |
1 other study available for suramin and Orchitis
| Article | Year |
|---|---|
Orchitis as an unusual manifestation of human African trypanosomiasis.
Topics: Adult; Humans; Male; Orchitis; Suramin; Trypanocidal Agents; Trypanosomiasis, African | 2006 |