suramin has been researched along with Neutropenia in 1 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Neutropenia: A decrease in the number of NEUTROPHILS found in the blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This paper presents a retrospective review of 6 cases of severe neutropenia attributed to suramin, the response to granulocyte-colony stimulating factor (G-CSF) and the possible mechanism." | 7.69 | Suramin-induced neutropenia. ( Dawson, NA; Figg, WD; Headlee, DJ; Lush, RM; Steinberg, SM; Tompkins, AC, 1996) |
| "This paper presents a retrospective review of 6 cases of severe neutropenia attributed to suramin, the response to granulocyte-colony stimulating factor (G-CSF) and the possible mechanism." | 3.69 | Suramin-induced neutropenia. ( Dawson, NA; Figg, WD; Headlee, DJ; Lush, RM; Steinberg, SM; Tompkins, AC, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dawson, NA | 1 |
| Lush, RM | 1 |
| Steinberg, SM | 1 |
| Tompkins, AC | 1 |
| Headlee, DJ | 1 |
| Figg, WD | 1 |
1 other study available for suramin and Neutropenia
| Article | Year |
|---|---|
Suramin-induced neutropenia.
Topics: Adult; Aged; Antineoplastic Agents; Bayes Theorem; Fibroblast Growth Factor 2; Granulocyte Colony-St | 1996 |