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suramin and Neutropenia

suramin has been researched along with Neutropenia in 1 studies

Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.

Neutropenia: A decrease in the number of NEUTROPHILS found in the blood.

Research Excerpts

ExcerptRelevanceReference
"This paper presents a retrospective review of 6 cases of severe neutropenia attributed to suramin, the response to granulocyte-colony stimulating factor (G-CSF) and the possible mechanism."7.69Suramin-induced neutropenia. ( Dawson, NA; Figg, WD; Headlee, DJ; Lush, RM; Steinberg, SM; Tompkins, AC, 1996)
"This paper presents a retrospective review of 6 cases of severe neutropenia attributed to suramin, the response to granulocyte-colony stimulating factor (G-CSF) and the possible mechanism."3.69Suramin-induced neutropenia. ( Dawson, NA; Figg, WD; Headlee, DJ; Lush, RM; Steinberg, SM; Tompkins, AC, 1996)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dawson, NA1
Lush, RM1
Steinberg, SM1
Tompkins, AC1
Headlee, DJ1
Figg, WD1

Other Studies

1 other study available for suramin and Neutropenia

ArticleYear
Suramin-induced neutropenia.
    European journal of cancer (Oxford, England : 1990), 1996, Volume: 32A, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents; Bayes Theorem; Fibroblast Growth Factor 2; Granulocyte Colony-St

1996