Page last updated: 2024-11-04

suramin and Neuralgia

suramin has been researched along with Neuralgia in 2 studies

Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.

Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gadotti, VM1
Caballero, AG1
Berger, ND1
Gladding, CM1
Chen, L1
Pfeifer, TA1
Zamponi, GW1
Quasthoff, S1
Hartung, HP1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Investigation of the Effect of Chemotherapy-induced Peripheral Neuropathy (CIPN) on Sensory and Motor Function in Patients With Cancer[NCT04799080]72 participants (Actual)Observational2021-03-06Completed
The Use of Cryotherapy to Prevent Paclitaxel-induced Peripheral Neuropathy and Nail Changes in Women With Breast Cancer[NCT04558034]14 participants (Actual)Interventional2020-08-04Terminated (stopped due to Principal Investigator retired before study completed.)
Randomized Phase III Clinical Trial of Weekly Versus Tri-weekly Cisplatin Based Chemoradiation in Locally Advanced Cervical Cancer[NCT01561586]Phase 3374 participants (Anticipated)Interventional2012-03-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for suramin and Neuralgia

ArticleYear
Chemotherapy-induced peripheral neuropathy.
    Journal of neurology, 2002, Volume: 249, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug-Related Side Effects and

2002
Chemotherapy-induced peripheral neuropathy.
    Journal of neurology, 2002, Volume: 249, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug-Related Side Effects and

2002
Chemotherapy-induced peripheral neuropathy.
    Journal of neurology, 2002, Volume: 249, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug-Related Side Effects and

2002
Chemotherapy-induced peripheral neuropathy.
    Journal of neurology, 2002, Volume: 249, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug-Related Side Effects and

2002
Chemotherapy-induced peripheral neuropathy.
    Journal of neurology, 2002, Volume: 249, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug-Related Side Effects and

2002
Chemotherapy-induced peripheral neuropathy.
    Journal of neurology, 2002, Volume: 249, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug-Related Side Effects and

2002
Chemotherapy-induced peripheral neuropathy.
    Journal of neurology, 2002, Volume: 249, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug-Related Side Effects and

2002
Chemotherapy-induced peripheral neuropathy.
    Journal of neurology, 2002, Volume: 249, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug-Related Side Effects and

2002
Chemotherapy-induced peripheral neuropathy.
    Journal of neurology, 2002, Volume: 249, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug-Related Side Effects and

2002

Other Studies

1 other study available for suramin and Neuralgia

ArticleYear
Small organic molecule disruptors of Cav3.2 - USP5 interactions reverse inflammatory and neuropathic pain.
    Molecular pain, 2015, Mar-14, Volume: 11

    Topics: Analgesics; Animals; Calcium Channels, T-Type; Ganglia, Spinal; Humans; Hyperalgesia; Inflammation;

2015