suramin has been researched along with Lung Adenocarcinoma in 2 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Emodin is an anthraquinone derivative originally isolated from Chinese rhubarb, possesses anticancer properties." | 5.46 | Emodin Inhibits ATP-Induced Proliferation and Migration by Suppressing P2Y Receptors in Human Lung Adenocarcinoma Cells. ( Guan, R; Li, L; Shen, L; Song, N; Wang, X; Zhu, D, 2017) |
| "Suramin treatment before cisplatin administration reduced cisplatin-induced decreases in kidney function and injury." | 5.43 | Suramin protects from cisplatin-induced acute kidney injury. ( Arteel, GE; Beverly, LJ; Casson, L; Doll, MA; Dupre, TV; Jenson, AB; Kiefer, A; Megyesi, J; Saforo, D; Saurabh, K; Scherzer, MT; Schnellmann, RG; Shah, PP; Sharp, CN; Siow, D; Siskind, LJ, 2016) |
| "Emodin is an anthraquinone derivative originally isolated from Chinese rhubarb, possesses anticancer properties." | 1.46 | Emodin Inhibits ATP-Induced Proliferation and Migration by Suppressing P2Y Receptors in Human Lung Adenocarcinoma Cells. ( Guan, R; Li, L; Shen, L; Song, N; Wang, X; Zhu, D, 2017) |
| "Suramin treatment before cisplatin administration reduced cisplatin-induced decreases in kidney function and injury." | 1.43 | Suramin protects from cisplatin-induced acute kidney injury. ( Arteel, GE; Beverly, LJ; Casson, L; Doll, MA; Dupre, TV; Jenson, AB; Kiefer, A; Megyesi, J; Saforo, D; Saurabh, K; Scherzer, MT; Schnellmann, RG; Shah, PP; Sharp, CN; Siow, D; Siskind, LJ, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, X | 1 |
| Li, L | 1 |
| Guan, R | 1 |
| Zhu, D | 1 |
| Song, N | 1 |
| Shen, L | 1 |
| Dupre, TV | 1 |
| Doll, MA | 1 |
| Shah, PP | 1 |
| Sharp, CN | 1 |
| Kiefer, A | 1 |
| Scherzer, MT | 1 |
| Saurabh, K | 1 |
| Saforo, D | 1 |
| Siow, D | 1 |
| Casson, L | 1 |
| Arteel, GE | 1 |
| Jenson, AB | 1 |
| Megyesi, J | 1 |
| Schnellmann, RG | 1 |
| Beverly, LJ | 1 |
| Siskind, LJ | 1 |
2 other studies available for suramin and Lung Adenocarcinoma
| Article | Year |
|---|---|
Emodin Inhibits ATP-Induced Proliferation and Migration by Suppressing P2Y Receptors in Human Lung Adenocarcinoma Cells.
Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Adenosine Triphosphate; bcl-2-Associated X Prote | 2017 |
Suramin protects from cisplatin-induced acute kidney injury.
Topics: Acute Kidney Injury; Adenocarcinoma; Adenocarcinoma of Lung; Animals; Apoptosis; Cell Line, Tumor; C | 2016 |