Page last updated: 2024-11-04

suramin and Liver Diseases

suramin has been researched along with Liver Diseases in 2 studies

Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.

Liver Diseases: Pathological processes of the LIVER.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Szende, B1
Lapis, K1
Jeney, A1
Simon, K1
Ordög, A1
Moldvay, J1
Horne, MK1
Stein, CA1
LaRocca, RV1
Myers, CE1

Other Studies

2 other studies available for suramin and Liver Diseases

ArticleYear
Liver damaging effect of suramin in normal and carbon-tetrachloride treated rats.
    Toxicologic pathology, 1991, Volume: 19, Issue:3

    Topics: Animals; Body Weight; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Drug Synergism;

1991
Circulating glycosaminoglycan anticoagulants associated with suramin treatment.
    Blood, 1988, Volume: 71, Issue:2

    Topics: Adult; Anticoagulants; Blood Coagulation; Blood Coagulation Disorders; Chromatography, DEAE-Cellulos

1988