Page last updated: 2024-11-04

suramin and Leg Ulcer

suramin has been researched along with Leg Ulcer in 1 studies

Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.

Leg Ulcer: Ulceration of the skin and underlying structures of the lower extremity. About 90% of the cases are due to venous insufficiency (VARICOSE ULCER), 5% to arterial disease, and the remaining 5% to other causes.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Faust, SN1
Woodrow, CJ1
Patel, S1
Snape, M1
Chiodini, PL1
Tudor-Williams, G1
Hermione Lyall, EG1

Other Studies

1 other study available for suramin and Leg Ulcer

ArticleYear
Sleeping sickness in brothers in london.
    The Pediatric infectious disease journal, 2004, Volume: 23, Issue:9

    Topics: Adolescent; Animals; Child; Dose-Response Relationship, Drug; Drug Administration Schedule; Follow-U

2004