Page last updated: 2024-11-04

suramin and Keratoacanthoma

suramin has been researched along with Keratoacanthoma in 1 studies

Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.

Keratoacanthoma: A benign, non-neoplastic, usually self-limiting epithelial lesion closely resembling squamous cell carcinoma clinically and histopathologically. It occurs in solitary, multiple, and eruptive forms. The solitary and multiple forms occur on sunlight exposed areas and are identical histologically; they affect primarily white males. The eruptive form usually involves both sexes and appears as a generalized papular eruption.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kobayashi, K1
Pezen, DS1
Vogelzang, NJ1
Medenica, M1
Janisch, L1
Ratain, M1
Vokes, EE1
Soltani, K1

Other Studies

1 other study available for suramin and Keratoacanthoma

ArticleYear
Keratoacanthomas and skin neoplasms associated with suramin therapy.
    Archives of dermatology, 1996, Volume: 132, Issue:1

    Topics: Aged; Antineoplastic Agents; Humans; Keratoacanthoma; Male; Middle Aged; Skin Neoplasms; Suramin

1996