Page last updated: 2024-11-04

suramin and Johne Disease

suramin has been researched along with Johne Disease in 1 studies

Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
CHANDLER, RL1

Other Studies

1 other study available for suramin and Johne Disease

ArticleYear
Infection of laboratory animals with Mycobacterium johnei. I. Infection in Swiss white mice and its modification by suramin and cortisone.
    Journal of comparative pathology, 1961, Volume: 71

    Topics: Animals; Animals, Laboratory; Cortisone; Mice; Mycobacterium avium subsp. paratuberculosis; Paratube

1961