suramin has been researched along with Itching in 1 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ten male patients with onchocerciasis received six weekly infusions of suramin according to the WHO-recommended regimen." | 9.08 | Clinical pharmacokinetics of suramin in patients with onchocerciasis. ( Chijioke, CP; Fleckenstein, LL; Mbah, AU; Nwonu, P; Okonkwo, PO; Umeh, RE, 1998) |
| "Ten male patients with onchocerciasis received six weekly infusions of suramin according to the WHO-recommended regimen." | 5.08 | Clinical pharmacokinetics of suramin in patients with onchocerciasis. ( Chijioke, CP; Fleckenstein, LL; Mbah, AU; Nwonu, P; Okonkwo, PO; Umeh, RE, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chijioke, CP | 1 |
| Umeh, RE | 1 |
| Mbah, AU | 1 |
| Nwonu, P | 1 |
| Fleckenstein, LL | 1 |
| Okonkwo, PO | 1 |
1 trial available for suramin and Itching
| Article | Year |
|---|---|
Clinical pharmacokinetics of suramin in patients with onchocerciasis.
Topics: Adult; Animals; Antinematodal Agents; Exanthema; Foot; Humans; Hypopigmentation; Male; Metabolic Cle | 1998 |