suramin has been researched along with Intraocular Pressure in 3 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Suramin was applied with concentrations ranging from 10 mg/ml to 333 mg/ml once during surgery and four times following surgery." | 5.30 | Suramin inhibits wound healing following filtering procedures for glaucoma. ( Chévez-Barrios, P; Feldman, RM; Lieberman, MW; Mietz, H, 1998) |
| "Suramin was applied with concentrations ranging from 10 mg/ml to 333 mg/ml once during surgery and four times following surgery." | 1.30 | Suramin inhibits wound healing following filtering procedures for glaucoma. ( Chévez-Barrios, P; Feldman, RM; Lieberman, MW; Mietz, H, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pintor, J | 1 |
| Peral, A | 1 |
| Peláez, T | 1 |
| Martín, S | 1 |
| Hoyle, CH | 1 |
| Akman, A | 1 |
| Bilezikçi, B | 1 |
| Küçükerdönmez, C | 1 |
| Demirhan, B | 1 |
| Aydin, P | 1 |
| Mietz, H | 1 |
| Chévez-Barrios, P | 1 |
| Feldman, RM | 1 |
| Lieberman, MW | 1 |
3 other studies available for suramin and Intraocular Pressure
| Article | Year |
|---|---|
Presence of diadenosine polyphosphates in the aqueous humor: their effect on intraocular pressure.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Aqueous Humor; Chromat | 2003 |
Suramin modulates wound healing of rabbit conjunctiva after trabeculectomy: comparison with mitomycin C.
Topics: Animals; Antimetabolites; Conjunctiva; Growth Substances; Intraocular Pressure; Intraoperative Care; | 2003 |
Suramin inhibits wound healing following filtering procedures for glaucoma.
Topics: Animals; Electromyography; Female; Fibrosis; Filtering Surgery; Glaucoma; Intraocular Pressure; Rabb | 1998 |