Page last updated: 2024-11-04

suramin and Infarct

suramin has been researched along with Infarct in 1 studies

Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.

Research Excerpts

ExcerptRelevanceReference
"Focal brain ischemia was produced by unilateral occlusion and transection of the middle cerebral artery (MCAT) and bilateral occlusion of the common carotid arteries (CCA)."5.31Suramin reduces infarct volume in a model of focal brain ischemia in rats. ( Jones, SC; Kharlamov, A; Kim, DK, 2002)
"Focal brain ischemia was produced by unilateral occlusion and transection of the middle cerebral artery (MCAT) and bilateral occlusion of the common carotid arteries (CCA)."1.31Suramin reduces infarct volume in a model of focal brain ischemia in rats. ( Jones, SC; Kharlamov, A; Kim, DK, 2002)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kharlamov, A1
Jones, SC1
Kim, DK1

Other Studies

1 other study available for suramin and Infarct

ArticleYear
Suramin reduces infarct volume in a model of focal brain ischemia in rats.
    Experimental brain research, 2002, Volume: 147, Issue:3

    Topics: Animals; Brain; Brain Ischemia; Carotid Arteries; Disease Models, Animal; Dose-Response Relationship

2002