suramin has been researched along with Hypertrophy in 3 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shitara, A | 1 |
| Tanimura, A | 1 |
| Sato, A | 1 |
| Tojyo, Y | 1 |
| Ricciardi, MP | 1 |
| Soldani, P | 1 |
| Paparelli, A | 1 |
| Gesi, M | 1 |
| Pellegrini, A | 1 |
| Lluel, P | 1 |
| Barras, M | 1 |
| Palea, S | 1 |
3 other studies available for suramin and Hypertrophy
| Article | Year |
|---|---|
Spontaneous Ca2+ oscillations via purinergic receptors elicit transient cell swelling in rat parotid ducts.
Topics: Adenosine Triphosphate; Animals; Calcium; Electrolytes; Hypertrophy; Parotid Gland; Purinergic Antag | 2009 |
Morphohistochemical relationships between adrenal cortex and major salivary glands in response to chronic suramin treatment.
Topics: 3-Hydroxysteroid Dehydrogenases; Adrenal Cortex; Animals; Cholesterol; Humans; Hypertrophy; Lymphocy | 1995 |
Cholinergic and purinergic contribution to the micturition reflex in conscious rats with long-term bladder outlet obstruction.
Topics: Animals; Atropine; Cholinergic Fibers; Chronic Disease; Drug Combinations; Electric Stimulation; Fem | 2002 |