suramin has been researched along with Hypersensitivity in 2 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Hypersensitivity: Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (50.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Ganapaty, S | 1 |
Chandrashekhar, VM | 1 |
Narsu, ML | 1 |
JANCSO, N | 1 |
JANCSO-GABOR, A | 1 |
2 other studies available for suramin and Hypersensitivity
Article | Year |
---|---|
Evaluation of anti-allergic activity of gossypin and suramin in mast cell-mediated allergy model.
Topics: Anaphylaxis; Animals; Anti-Allergic Agents; Antipruritics; Ascitic Fluid; Bronchoalveolar Lavage Flu | 2010 |
[Visualization of tissue immune reactions].
Topics: Humans; Hypersensitivity; Suramin | 1952 |