suramin has been researched along with Hypercapnia in 2 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Hypercapnia: A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wenker, IC | 1 |
| Sobrinho, CR | 1 |
| Takakura, AC | 1 |
| Moreira, TS | 1 |
| Mulkey, DK | 1 |
| Niane, LM | 1 |
| Joseph, V | 1 |
| Bairam, A | 1 |
2 other studies available for suramin and Hypercapnia
| Article | Year |
|---|---|
Regulation of ventral surface CO2/H+-sensitive neurons by purinergic signalling.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Blood Pressure; Brain Stem; Calcium; Carbenoxolo | 2012 |
Systemic blockade of nicotinic and purinergic receptors inhibits ventilation and increases apnoea frequency in newborn rats.
Topics: Animals; Animals, Newborn; Apnea; Carbon Dioxide; Drug Therapy, Combination; Female; Hexamethonium; | 2012 |