suramin has been researched along with HIV Coinfection in 4 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tan, S | 1 |
| Li, JQ | 1 |
| Cheng, H | 1 |
| Li, Z | 1 |
| Lan, Y | 1 |
| Zhang, TT | 1 |
| Yang, ZC | 1 |
| Li, W | 1 |
| Qi, T | 1 |
| Qiu, YR | 1 |
| Chen, Z | 1 |
| Li, L | 1 |
| Liu, SW | 1 |
| Fulcher, AJ | 1 |
| Jans, DA | 1 |
| Opocher, G | 1 |
| Mantero, F | 1 |
| Kassack, M | 1 |
| Nickel, P | 1 |
2 reviews available for suramin and HIV Coinfection
| Article | Year |
|---|---|
The HIV-1 Tat transactivator protein: a therapeutic target?
Topics: Drug Delivery Systems; Gene Expression Regulation, Viral; Gene Products, rev; Gene Products, tat; HI | 2003 |
Adrenal complications of HIV infection.
Topics: Acquired Immunodeficiency Syndrome; Adrenal Cortex; Adrenal Gland Diseases; AIDS-Related Opportunist | 1994 |
2 other studies available for suramin and HIV Coinfection
| Article | Year |
|---|---|
The anti-parasitic drug suramin potently inhibits formation of seminal amyloid fibrils and their interaction with HIV-1.
Topics: Adult; Amyloid; Animals; Anti-HIV Agents; Anti-Retroviral Agents; Healthy Volunteers; HIV Infections | 2019 |
Stability of suramin in aqueous solution; possible implications for the search for suramin metabolites in patients.
Topics: Drug Stability; HIV Infections; Humans; Kinetics; Solutions; Suramin; Temperature | 1996 |