suramin has been researched along with Erythema in 2 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Erythema: Redness of the skin produced by congestion of the capillaries. This condition may result from a variety of disease processes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Human African trypanosomiasis (sleeping sickness) is a parasitic infection transmitted by day-biting tsetse flies." | 1.33 | African trypanosomiasis in a British soldier. ( Croft, AM; Friend, HM; Jackson, CJ; Minton, EJ, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Croft, AM | 1 |
| Jackson, CJ | 1 |
| Friend, HM | 1 |
| Minton, EJ | 1 |
| Moore, AC | 1 |
| Ryan, ET | 1 |
| Waldron, MA | 1 |
2 other studies available for suramin and Erythema
| Article | Year |
|---|---|
African trypanosomiasis in a British soldier.
Topics: Adult; Antinematodal Agents; Chancre; Erythema; Fever; Humans; Injections; Male; Military Personnel; | 2006 |
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 20-2002. A 37-year-old man with fever, hepatosplenomegaly, and a cutaneous foot lesion after a trip to Africa.
Topics: Adult; Africa; Animals; Anthrax; Blood; Cerebrospinal Fluid; Diagnosis, Differential; Erythema; Feve | 2002 |