suramin has been researched along with Electrolytes in 4 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Electrolytes: Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study was carried out to evaluate if inhibited angiogenesis by Suramin injections in early pregnancy may cause a condition resembling pre-eclampsia in rats." | 7.73 | Placental dysfunction in Suramin-treated rats--a new model for pre-eclampsia. ( Eriksson, UJ; Jansson, L; Lindeberg, S; Naessén, T; Nash, P; Olovsson, M; Wentzel, P, 2005) |
| "In both rat strains Suramin caused fetal growth retardation, decreased placental blood flow, and increased placental concentration of the isoprostane 8-iso-PGF(2alpha)." | 3.73 | Placental dysfunction in Suramin-treated rats: impact of maternal diabetes and effects of antioxidative treatment. ( Eriksson, UJ; Nash, P; Olovsson, M, 2005) |
| " This study was carried out to evaluate if inhibited angiogenesis by Suramin injections in early pregnancy may cause a condition resembling pre-eclampsia in rats." | 3.73 | Placental dysfunction in Suramin-treated rats--a new model for pre-eclampsia. ( Eriksson, UJ; Jansson, L; Lindeberg, S; Naessén, T; Nash, P; Olovsson, M; Wentzel, P, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shitara, A | 1 |
| Tanimura, A | 1 |
| Sato, A | 1 |
| Tojyo, Y | 1 |
| Quaglia, M | 1 |
| De Lorenzi, E | 1 |
| Nash, P | 2 |
| Olovsson, M | 2 |
| Eriksson, UJ | 2 |
| Wentzel, P | 1 |
| Lindeberg, S | 1 |
| Naessén, T | 1 |
| Jansson, L | 1 |
4 other studies available for suramin and Electrolytes
| Article | Year |
|---|---|
Spontaneous Ca2+ oscillations via purinergic receptors elicit transient cell swelling in rat parotid ducts.
Topics: Adenosine Triphosphate; Animals; Calcium; Electrolytes; Hypertrophy; Parotid Gland; Purinergic Antag | 2009 |
Capillary electrophoresis in drug discovery.
Topics: beta 2-Microglobulin; Drug Discovery; Drug Evaluation, Preclinical; Electrolytes; Electrophoresis, C | 2009 |
Placental dysfunction in Suramin-treated rats: impact of maternal diabetes and effects of antioxidative treatment.
Topics: Animals; Antioxidants; Blood Pressure; Body Weight; Diabetes Mellitus, Experimental; Electrolytes; E | 2005 |
Placental dysfunction in Suramin-treated rats--a new model for pre-eclampsia.
Topics: Angiogenesis Inhibitors; Animals; Blood Pressure; Disease Models, Animal; Electrolytes; Endothelin-1 | 2005 |