suramin has been researched along with Ebola Hemorrhagic Fever in 2 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It causes the Ebola virus disease (EDV), formerly known as Ebola hemorrhagic fever in humans and has a mortality rate of up to 70 %." | 1.43 | Suramin is a potent inhibitor of Chikungunya and Ebola virus cell entry. ( Beck, S; Becker, S; Biedenkopf, N; Henß, L; Schnierle, BS; Sliva, K; Weber, C; Weidner, T, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yuan, B | 1 |
| Peng, Q | 1 |
| Cheng, J | 1 |
| Wang, M | 1 |
| Zhong, J | 1 |
| Qi, J | 1 |
| Gao, GF | 1 |
| Shi, Y | 1 |
| Henß, L | 1 |
| Beck, S | 1 |
| Weidner, T | 1 |
| Biedenkopf, N | 1 |
| Sliva, K | 1 |
| Weber, C | 1 |
| Becker, S | 1 |
| Schnierle, BS | 1 |
2 other studies available for suramin and Ebola Hemorrhagic Fever
| Article | Year |
|---|---|
Structure of the Ebola virus polymerase complex.
Topics: Antiviral Agents; Catalytic Domain; Cryoelectron Microscopy; DNA-Directed RNA Polymerases; Ebolaviru | 2022 |
Suramin is a potent inhibitor of Chikungunya and Ebola virus cell entry.
Topics: Animals; Antiviral Agents; Cell Line; Chikungunya Fever; Chikungunya virus; Ebolavirus; Hemorrhagic | 2016 |