Page last updated: 2024-11-04

suramin and EHS Tumor

suramin has been researched along with EHS Tumor in 4 studies

Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
WILLIAMS, WL1
Morris, AD1
Léonce, S1
Guilbaud, N1
Tucker, GC1
Pérez, V1
Jan, M1
Cordi, AA1
Pierré, A1
Atassi, G1
Beauchamp, RD1
Sheng, HM1
Bascom, CC1
Miller, DA1
Lyons, RM1
Torre-Amione, G1
Moses, HL1
Petcu, DJ1
Aldrich, CE1
Coates, L1
Taylor, JM1
Mason, WS1

Other Studies

4 other studies available for suramin and EHS Tumor

ArticleYear
The effects of suramin (germanin), azo dyes, and vasodilators on mice with transplanted lymphosarcomas.
    Cancer research, 1946, Volume: 6

    Topics: Animals; Azo Compounds; Coloring Agents; Lymphoma, Non-Hodgkin; Mice; Sarcoma, Experimental; Suramin

1946
Eriochrome Black T, structurally related to suramin, inhibits angiogenesis and tumor growth in vivo.
    Anti-cancer drugs, 1997, Volume: 8, Issue:8

    Topics: Animals; Antineoplastic Agents; Azo Compounds; Cell Division; Drug Screening Assays, Antitumor; Fema

1997
Phenotypic alterations in fibroblasts and fibrosarcoma cells that overexpress latent transforming growth factor-beta 1.
    Endocrinology, 1992, Volume: 130, Issue:5

    Topics: Animals; Blotting, Northern; Cell Line; Embryo, Mammalian; Fibroblasts; Fibrosarcoma; Gene Expressio

1992
Suramin inhibits in vitro infection by duck hepatitis B virus, Rous sarcoma virus, and hepatitis delta virus.
    Virology, 1988, Volume: 167, Issue:2

    Topics: Animals; Avian Sarcoma Viruses; Cells, Cultured; Chick Embryo; Hepatitis B virus; Hepatitis Delta Vi

1988