suramin has been researched along with EHS Tumor in 4 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| WILLIAMS, WL | 1 |
| Morris, AD | 1 |
| Léonce, S | 1 |
| Guilbaud, N | 1 |
| Tucker, GC | 1 |
| Pérez, V | 1 |
| Jan, M | 1 |
| Cordi, AA | 1 |
| Pierré, A | 1 |
| Atassi, G | 1 |
| Beauchamp, RD | 1 |
| Sheng, HM | 1 |
| Bascom, CC | 1 |
| Miller, DA | 1 |
| Lyons, RM | 1 |
| Torre-Amione, G | 1 |
| Moses, HL | 1 |
| Petcu, DJ | 1 |
| Aldrich, CE | 1 |
| Coates, L | 1 |
| Taylor, JM | 1 |
| Mason, WS | 1 |
4 other studies available for suramin and EHS Tumor
| Article | Year |
|---|---|
The effects of suramin (germanin), azo dyes, and vasodilators on mice with transplanted lymphosarcomas.
Topics: Animals; Azo Compounds; Coloring Agents; Lymphoma, Non-Hodgkin; Mice; Sarcoma, Experimental; Suramin | 1946 |
Eriochrome Black T, structurally related to suramin, inhibits angiogenesis and tumor growth in vivo.
Topics: Animals; Antineoplastic Agents; Azo Compounds; Cell Division; Drug Screening Assays, Antitumor; Fema | 1997 |
Phenotypic alterations in fibroblasts and fibrosarcoma cells that overexpress latent transforming growth factor-beta 1.
Topics: Animals; Blotting, Northern; Cell Line; Embryo, Mammalian; Fibroblasts; Fibrosarcoma; Gene Expressio | 1992 |
Suramin inhibits in vitro infection by duck hepatitis B virus, Rous sarcoma virus, and hepatitis delta virus.
Topics: Animals; Avian Sarcoma Viruses; Cells, Cultured; Chick Embryo; Hepatitis B virus; Hepatitis Delta Vi | 1988 |