suramin has been researched along with E coli Infections in 2 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Urosepsis is a severe condition often caused by Escherichia coli that spontaneously have ascended the urinary tract to the kidneys causing pyelonephritis and potentially bacteraemia." | 1.51 | P2X ( Christensen, MG; Fagerberg, SK; Greve, AS; Johnsen, N; Praetorius, HA; Skals, M, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Skals, M | 1 |
| Greve, AS | 1 |
| Fagerberg, SK | 1 |
| Johnsen, N | 1 |
| Christensen, MG | 1 |
| Praetorius, HA | 1 |
| Arvidsson, I | 1 |
| Ståhl, AL | 1 |
| Hedström, MM | 1 |
| Kristoffersson, AC | 1 |
| Rylander, C | 1 |
| Westman, JS | 1 |
| Storry, JR | 1 |
| Olsson, ML | 1 |
| Karpman, D | 1 |
2 other studies available for suramin and E coli Infections
| Article | Year |
|---|---|
P2X
Topics: Animals; Benzenesulfonates; Blood Platelets; Escherichia coli Infections; Hemolysin Proteins; Male; | 2019 |
Shiga toxin-induced complement-mediated hemolysis and release of complement-coated red blood cell-derived microvesicles in hemolytic uremic syndrome.
Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Child; Child, Preschool; Coated Vesicles; Complement | 2015 |