suramin has been researched along with Drug-Related Side Effects and Adverse Reactions in 1 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Drug-Related Side Effects and Adverse Reactions: Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chemically-induced adverse conditions due to toxicity, DRUG INTERACTIONS, and metabolic effects of pharmaceuticals.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Quasthoff, S | 1 |
| Hartung, HP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Investigation of the Effect of Chemotherapy-induced Peripheral Neuropathy (CIPN) on Sensory and Motor Function in Patients With Cancer[NCT04799080] | 72 participants (Actual) | Observational | 2021-03-06 | Completed | |||
| The Use of Cryotherapy to Prevent Paclitaxel-induced Peripheral Neuropathy and Nail Changes in Women With Breast Cancer[NCT04558034] | 14 participants (Actual) | Interventional | 2020-08-04 | Terminated (stopped due to Principal Investigator retired before study completed.) | |||
| Randomized Phase III Clinical Trial of Weekly Versus Tri-weekly Cisplatin Based Chemoradiation in Locally Advanced Cervical Cancer[NCT01561586] | Phase 3 | 374 participants (Anticipated) | Interventional | 2012-03-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for suramin and Drug-Related Side Effects and Adverse Reactions
| Article | Year |
|---|---|
Chemotherapy-induced peripheral neuropathy.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug-Related Side Effects and | 2002 |
Chemotherapy-induced peripheral neuropathy.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug-Related Side Effects and | 2002 |
Chemotherapy-induced peripheral neuropathy.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug-Related Side Effects and | 2002 |
Chemotherapy-induced peripheral neuropathy.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug-Related Side Effects and | 2002 |
Chemotherapy-induced peripheral neuropathy.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug-Related Side Effects and | 2002 |
Chemotherapy-induced peripheral neuropathy.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug-Related Side Effects and | 2002 |
Chemotherapy-induced peripheral neuropathy.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug-Related Side Effects and | 2002 |
Chemotherapy-induced peripheral neuropathy.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug-Related Side Effects and | 2002 |
Chemotherapy-induced peripheral neuropathy.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug-Related Side Effects and | 2002 |