suramin has been researched along with Diffuse Mixed Small and Large Cell Lymphoma in 3 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| WILLIAMS, WL | 1 |
| Cheson, BD | 2 |
| Arbuck, SG | 1 |
| Sorensen, JM | 1 |
| Christian, MC | 1 |
| Ho, P | 1 |
| Pluda, JM | 1 |
2 reviews available for suramin and Diffuse Mixed Small and Large Cell Lymphoma
| Article | Year |
|---|---|
New chemotherapeutic agents for the treatment of low-grade non-Hodgkin's lymphomas.
Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Depsipeptides; Galli | 1993 |
New drugs in non-Hodgkin's lymphoma.
Topics: Adenosine; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Bryostatins; Enzyme Inhibitors; | 1997 |
1 other study available for suramin and Diffuse Mixed Small and Large Cell Lymphoma
| Article | Year |
|---|---|
The effects of suramin (germanin), azo dyes, and vasodilators on mice with transplanted lymphosarcomas.
Topics: Animals; Azo Compounds; Coloring Agents; Lymphoma, Non-Hodgkin; Mice; Sarcoma, Experimental; Suramin | 1946 |