suramin has been researched along with Diabetes Mellitus in 3 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mahapatra, MK | 1 |
| Kumar, R | 1 |
| Kumar, M | 1 |
| Karczewska, J | 1 |
| Piwkowska, A | 1 |
| Rogacka, D | 1 |
| Stępiński, J | 1 |
| Angielski, S | 1 |
| Jankowski, M | 1 |
| Michno, A | 1 |
| Bielarczyk, H | 1 |
| Pawełczyk, T | 1 |
| Jankowska-Kulawy, A | 1 |
| Klimaszewska, J | 1 |
| Szutowicz, A | 1 |
3 other studies available for suramin and Diabetes Mellitus
| Article | Year |
|---|---|
Synthesis, biological evaluation and in silico studies of 5-(3-methoxybenzylidene)thiazolidine-2,4-dione analogues as PTP1B inhibitors.
Topics: Animals; Computer Simulation; Diabetes Mellitus; Drug Design; Enzyme Inhibitors; Humans; Hyperglycem | 2017 |
Purinergic modulation of glucose uptake into cultured rat podocytes: effect of diabetic milieu.
Topics: Adenosine Triphosphate; Animals; Biological Transport; Cells, Cultured; Deoxyglucose; Diabetes Melli | 2011 |
Alterations of adenine nucleotide metabolism and function of blood platelets in patients with diabetes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acids; Blood Platelets; Diabetes Mellitus; Dose | 2007 |