suramin has been researched along with Dermatitis Medicamentosa in 7 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
| Excerpt | Relevance | Reference |
|---|---|---|
| "(1) Suramin is of antineoplastic efficacy in the treatment of metastatic adrenocortical carcinoma." | 3.69 | Suramin in adrenocortical cancer: limited efficacy and serious toxicity. ( Allolio, B; Arlt, W; Reincke, M; Siekmann, L; Winkelmann, W, 1994) |
| "Suramin has long been used in the treatment of onchocerciasis and trypanosomiasis." | 1.29 | [Cutaneous drug reaction caused by suramin in 4 patients with metastatic prostate cancer]. ( Dieckmann, KP; Gollnick, H; Handke, A; Tebbe, B; Wichterich, K, 1994) |
| "In our population filariasis is mainly imported from central and western Africa, especially Cameroon." | 1.26 | [Filariasis in patients returned from the tropics. Studies on 64 cases]. ( Degrémont, A; Stürchler, D, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 6 (85.71) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lowitt, MH | 1 |
| Eisenberger, M | 1 |
| Sina, B | 1 |
| Kao, GF | 1 |
| Katz, SK | 1 |
| Medenica, MM | 1 |
| Kobayashi, K | 1 |
| Vogelzang, NJ | 1 |
| Soltani, K | 1 |
| Arlt, W | 1 |
| Reincke, M | 1 |
| Siekmann, L | 1 |
| Winkelmann, W | 1 |
| Allolio, B | 1 |
| Wichterich, K | 1 |
| Tebbe, B | 1 |
| Handke, A | 1 |
| Dieckmann, KP | 1 |
| Gollnick, H | 1 |
| Kenner, JR | 1 |
| Sperling, LC | 1 |
| Waselenko, J | 1 |
| Dawson, N | 1 |
| Sau, P | 1 |
| Moul, JW | 1 |
| Stürchler, D | 1 |
| Degrémont, A | 1 |
| O'Donnell, BP | 1 |
| Dawson, NA | 1 |
| Weiss, RB | 1 |
| Myers, CE | 1 |
| James, WD | 1 |
1 review available for suramin and Dermatitis Medicamentosa
| Article | Year |
|---|---|
Cutaneous eruptions from suramin. A clinical and histopathologic study of 60 patients.
Topics: Adult; Aged; Antineoplastic Agents; Drug Eruptions; Female; Humans; Male; Middle Aged; Prospective S | 1995 |
1 trial available for suramin and Dermatitis Medicamentosa
| Article | Year |
|---|---|
Cutaneous eruptions from suramin. A clinical and histopathologic study of 60 patients.
Topics: Adult; Aged; Antineoplastic Agents; Drug Eruptions; Female; Humans; Male; Middle Aged; Prospective S | 1995 |
6 other studies available for suramin and Dermatitis Medicamentosa
| Article | Year |
|---|---|
Erythema multiforme induced by suramin.
Topics: Aged; Drug Eruptions; Erythema Multiforme; Humans; Injections, Intravenous; Male; Prostatic Neoplasm | 1995 |
Suramin in adrenocortical cancer: limited efficacy and serious toxicity.
Topics: Adrenal Cortex Neoplasms; Adult; Aged; Blood Coagulation; Bone Marrow; Carcinoma; Drug Eruptions; Fe | 1994 |
[Cutaneous drug reaction caused by suramin in 4 patients with metastatic prostate cancer].
Topics: Aged; Biopsy; Drug Eruptions; Drug Therapy, Combination; Humans; Infusions, Intravenous; Male; Middl | 1994 |
Suramin keratosis: a unique skin eruption in a patient receiving suramin for metastatic prostate cancer.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Drug Eruptions; Humans; Keratosis; Male; Prostatic Neop | 1997 |
[Filariasis in patients returned from the tropics. Studies on 64 cases].
Topics: Adult; Africa, Western; Diethylcarbamazine; Drug Eruptions; Eosinophilia; Female; Filariasis; Humans | 1976 |
Suramin-induced skin reactions.
Topics: Carcinoma; Drug Eruptions; Drug Evaluation; Humans; Infusions, Intravenous; Male; Prostatic Neoplasm | 1992 |