suramin has been researched along with Coronary Restenosis in 1 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Coronary Restenosis: Recurrent narrowing or constriction of a coronary artery following surgical procedures performed to alleviate a prior obstruction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Suramin is known to inhibit proliferation of various tumor cells." | 1.31 | Suramin inhibits proliferation of human arterial smooth muscle cells in vitro: potential drug for prevention of restenosis by local drug delivery. ( Bienert, H; Engisch, R; Günther, RW; Schürmann, K; vom Dahl, J; Vorwerk, D; Voss, M, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Engisch, R | 1 |
| Schürmann, K | 1 |
| Bienert, H | 1 |
| vom Dahl, J | 1 |
| Voss, M | 1 |
| Günther, RW | 1 |
| Vorwerk, D | 1 |
1 other study available for suramin and Coronary Restenosis
| Article | Year |
|---|---|
Suramin inhibits proliferation of human arterial smooth muscle cells in vitro: potential drug for prevention of restenosis by local drug delivery.
Topics: Arteries; Cell Culture Techniques; Cell Division; Cell Survival; Coronary Restenosis; Drug Delivery | 2000 |