suramin has been researched along with Coronary Disease in 2 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gergs, U | 1 |
| Boknik, P | 1 |
| Schmitz, W | 1 |
| Simm, A | 1 |
| Silber, RE | 1 |
| Neumann, J | 1 |
| Gray, TJ | 1 |
| Strauss, BH | 1 |
| Hinek, A | 1 |
2 other studies available for suramin and Coronary Disease
| Article | Year |
|---|---|
A positive inotropic effect of ATP in the human cardiac atrium.
Topics: Adenosine A1 Receptor Antagonists; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyc | 2008 |
Inhibitory mechanisms by which suramin may attenuate neointimal formation after balloon angioplasty.
Topics: Angioplasty, Balloon; Animals; Antineoplastic Agents; Cell Culture Techniques; Cell Division; Cell M | 1999 |