Page last updated: 2024-11-04

suramin and Chancre

suramin has been researched along with Chancre in 3 studies

Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.

Chancre: The primary sore of syphilis, a painless indurated, eroded papule, occurring at the site of entry of the infection.

Research Excerpts

ExcerptRelevanceReference
" He presented with an inoculation chancre and was treated with suramin within four days of fever onset."3.78Human African trypanosomiasis in a Belgian traveller returning from the Masai Mara area, Kenya, February 2012. ( Asselman, V; Clerinx, J; Lejon, V; Maes, MB; Van de Casteele, S; Vlieghe, E, 2012)
"In January 2012, a case of Human African Trypanosomiasis (HAT) has been identified in Germany in a traveller returning from the Masai Mara area in Kenya."1.38Trypanosoma brucei rhodesiense infection in a German traveller returning from the Masai Mara area, Kenya, January 2012. ( Brodt, HR; Gottig, S; Just-Nuebling, G; Kleine, C; Wichelhaus, T; Wolf, T, 2012)
"Human African trypanosomiasis (sleeping sickness) is a parasitic infection transmitted by day-biting tsetse flies."1.33African trypanosomiasis in a British soldier. ( Croft, AM; Friend, HM; Jackson, CJ; Minton, EJ, 2006)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wolf, T1
Wichelhaus, T1
Gottig, S1
Kleine, C1
Brodt, HR1
Just-Nuebling, G1
Clerinx, J1
Vlieghe, E1
Asselman, V1
Van de Casteele, S1
Maes, MB1
Lejon, V1
Croft, AM1
Jackson, CJ1
Friend, HM1
Minton, EJ1

Other Studies

3 other studies available for suramin and Chancre

ArticleYear
Trypanosoma brucei rhodesiense infection in a German traveller returning from the Masai Mara area, Kenya, January 2012.
    Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2012, Mar-08, Volume: 17, Issue:10

    Topics: Animals; Chancre; Diagnosis, Differential; Fever; Fluorescent Antibody Technique; Germany; Headache;

2012
Human African trypanosomiasis in a Belgian traveller returning from the Masai Mara area, Kenya, February 2012.
    Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2012, Mar-08, Volume: 17, Issue:10

    Topics: Belgium; Chancre; Fever; Headache; Humans; Kenya; Male; Polymerase Chain Reaction; Suramin; Travel;

2012
African trypanosomiasis in a British soldier.
    Journal of the Royal Army Medical Corps, 2006, Volume: 152, Issue:3

    Topics: Adult; Antinematodal Agents; Chancre; Erythema; Fever; Humans; Injections; Male; Military Personnel;

2006