suramin has been researched along with Cell Transformation, Viral in 7 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Cell Transformation, Viral: An inheritable change in cells manifested by changes in cell division and growth and alterations in cell surface properties. It is induced by infection with a transforming virus.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Franck, X | 1 |
| Fournet, A | 1 |
| Prina, E | 1 |
| Mahieux, R | 1 |
| Hocquemiller, R | 1 |
| Figadère, B | 1 |
| Cook, JR | 1 |
| Wang, DY | 1 |
| Chen, JK | 1 |
| Boensch, C | 1 |
| Huang, SS | 2 |
| Connolly, DT | 1 |
| Huang, JS | 2 |
| Lokeshwar, VB | 1 |
| De Clercq, E | 2 |
| Balzarini, J | 2 |
| Mitsuya, H | 1 |
| Broder, S | 1 |
| Betsholtz, C | 1 |
| Johnsson, A | 1 |
| Heldin, CH | 1 |
| Westermark, B | 1 |
7 other studies available for suramin and Cell Transformation, Viral
| Article | Year |
|---|---|
Biological evaluation of substituted quinolines.
Topics: Animals; Antiparasitic Agents; Cell Line; Cell Transformation, Viral; Evaluation Studies as Topic; H | 2004 |
Nonresponsiveness of an SV40-transformed Balb/c-3T3 cell line to PDGF mitogenicity is correlated with an irreversible reduction in PDGF receptor number.
Topics: 3T3 Cells; Animals; Cell Transformation, Viral; Culture Media, Serum-Free; Down-Regulation; Epiderma | 1993 |
Cell surface retention sequence binding protein-1 interacts with the v-sis gene product and platelet-derived growth factor beta-type receptor in simian sarcoma virus-transformed cells.
Topics: 3T3 Cells; Animals; Cell Transformation, Viral; Fluorescent Antibody Technique, Indirect; Membrane P | 1999 |
Intracellular turnover, novel secretion, and mitogenically active intracellular forms of v-sis gene product in simian sarcoma virus-transformed cells. Implications for intracellular loop autocrine transformation.
Topics: Ammonium Chloride; Animals; Blotting, Western; Cell Line; Cell Transformation, Viral; Cytoplasm; End | 1990 |
In search of specific inhibitors of retrovirus replication.
Topics: Acquired Immunodeficiency Syndrome; Amidines; Animals; Antiviral Agents; Cell Transformation, Neopla | 1985 |
Comparative inhibitory effects of suramin and other selected compounds on the infectivity and replication of human T-cell lymphotropic virus (HTLV-III)/lymphadenopathy-associated virus (LAV).
Topics: Animals; Antiviral Agents; Cell Transformation, Viral; Cytopathogenic Effect, Viral; Deltaretrovirus | 1986 |
Efficient reversion of simian sarcoma virus-transformation and inhibition of growth factor-induced mitogenesis by suramin.
Topics: Animals; Avian Sarcoma Viruses; Calcium; Cell Cycle; Cell Transformation, Viral; Epidermal Growth Fa | 1986 |