suramin has been researched along with Cardiovascular Abnormalities in 1 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Cardiovascular Abnormalities: Congenital, inherited, or acquired anomalies of the CARDIOVASCULAR SYSTEM, including the HEART and BLOOD VESSELS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Suramin was injected into the coelomic cavity of chick embryos on incubation day (ID) 3." | 1.32 | Teratogenic effects of suramin on the chick embryo. ( Heinicke, F; Hesse, H; Männer, J; Seidl, W, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Männer, J | 1 |
| Seidl, W | 1 |
| Heinicke, F | 1 |
| Hesse, H | 1 |
1 other study available for suramin and Cardiovascular Abnormalities
| Article | Year |
|---|---|
Teratogenic effects of suramin on the chick embryo.
Topics: Animals; Cardiovascular Abnormalities; Chick Embryo; Digestive System Abnormalities; Eye Abnormaliti | 2003 |