suramin has been researched along with Cardiomyopathies in 2 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Cardiomyopathies: A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Oliveira Moreira, D | 1 |
| Pereira, JA | 1 |
| Taniguti, AP | 1 |
| Matsumura, CY | 1 |
| Ramos, LA | 1 |
| Areas, MA | 1 |
| Neto, HS | 1 |
| Marques, MJ | 1 |
| Shiono, T | 1 |
| Kodama, M | 1 |
| Hanawa, H | 1 |
| Fuse, K | 1 |
| Yamamoto, T | 1 |
| Aizawa, Y | 1 |
2 other studies available for suramin and Cardiomyopathies
| Article | Year |
|---|---|
Suramin attenuates dystrophin-deficient cardiomyopathy in the mdx mouse model of duchenne muscular dystrophy.
Topics: Age Factors; Analysis of Variance; Animals; Antineoplastic Agents; Cardiomyopathies; Creatine Kinase | 2013 |
Suppression of myocardial inflammation using suramin, a growth factor blocker.
Topics: Animals; Anti-Inflammatory Agents; Autoimmune Diseases; Cardiomyopathies; Cytokines; Growth Inhibito | 2002 |