suramin has been researched along with Carcinoma, Ehrlich Tumor in 3 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Carcinoma, Ehrlich Tumor: A transplantable, poorly differentiated malignant tumor which appeared originally as a spontaneous breast carcinoma in a mouse. It grows in both solid and ascitic forms.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pedersen, SF | 2 |
| Pedersen, S | 2 |
| Lambert, IH | 2 |
| Hoffmann, EK | 2 |
| Nilius, B | 1 |
| Osswald, H | 1 |
| Youssef, M | 1 |
3 other studies available for suramin and Carcinoma, Ehrlich Tumor
| Article | Year |
|---|---|
P2 receptor-mediated signal transduction in Ehrlich ascites tumor cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Amiloride; Animals; Calciu | 1998 |
Mechanical stress induces release of ATP from Ehrlich ascites tumor cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Carcinoma, Ehrlich Tumor; Charybdotoxin; Purinergic P2 Rec | 1999 |
Suramin enhancement of the chemotherapeutic actions of cyclophosphamide or adriamycin of intramuscularly-implanted Ehrlich carcinoma.
Topics: Animals; Antineoplastic Agents; Biological Transport, Active; Carcinoma, Ehrlich Tumor; Cell Membran | 1979 |