suramin has been researched along with Carcinogenesis in 1 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
Carcinogenesis: The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Su, L | 1 |
| Bryan, N | 1 |
| Battista, S | 1 |
| Freitas, J | 1 |
| Garabedian, A | 1 |
| D'Alessio, F | 1 |
| Romano, M | 1 |
| Falanga, F | 1 |
| Fusco, A | 1 |
| Kos, L | 1 |
| Chambers, J | 1 |
| Fernandez-Lima, F | 1 |
| Chapagain, PP | 1 |
| Vasile, S | 1 |
| Smith, L | 1 |
| Leng, F | 1 |
1 other study available for suramin and Carcinogenesis
| Article | Year |
|---|---|
Identification of HMGA2 inhibitors by AlphaScreen-based ultra-high-throughput screening assays.
Topics: Adipogenesis; Amino Acid Motifs; Base Sequence; Binding Sites; Carcinogenesis; DNA; DNA-Binding Prot | 2020 |