suramin has been researched along with Cancer of Cervix in 2 studies
Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cell lines used were as follows: cervical cancer (HeLa), mammary cancer (MCF-7), bladder cancer (EJ), hepatoma (HuH-7, PLC/PRF/5), embryonal carcinoma (PA-1), and three in vitro transformed human fibroblast lines (KMST-6, SUSM-1, and VA-13)." | 1.28 | [Effects of suramin on cell proliferation of various types of human malignant cells]. ( Bai, LY; Miyazaki, M; Namba, M, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weckbecker, G | 1 |
| Liu, R | 1 |
| Tolcsvai, L | 1 |
| Bai, LY | 1 |
| Miyazaki, M | 1 |
| Namba, M | 1 |
2 other studies available for suramin and Cancer of Cervix
| Article | Year |
|---|---|
Intradermal angiogenesis in nude mice induced by human tumor cells or b-FGF.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Carcinoma, Squamous Cell; Cell Line; Female; Fibroblast G | 1992 |
[Effects of suramin on cell proliferation of various types of human malignant cells].
Topics: Breast Neoplasms; Carcinoma, Hepatocellular; Cell Division; Female; Humans; Liver Neoplasms; Male; S | 1991 |