Page last updated: 2024-11-04

suramin and Bruise

suramin has been researched along with Bruise in 2 studies

Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.

Research Excerpts

ExcerptRelevanceReference
"Suramin treatment initiated at 2 weeks post-injury was observed to promote muscle regeneration and muscle strength, and to decrease fibrosis."3.78Timing of the administration of suramin treatment after muscle injury. ( Fu, FH; Gharaibeh, B; Huard, J; Li, Y; Nozaki, M; Ota, S; Terada, S; Uehara, K, 2012)
"Suramin enhances muscle healing by both stimulating muscle regeneration and preventing fibrosis in contused skeletal muscle."3.74Improved muscle healing after contusion injury by the inhibitory effect of suramin on myostatin, a negative regulator of muscle growth. ( Ambrosio, F; Fu, FH; Huard, J; Li, Y; Nozaki, M; Uehara, K; Zhu, J, 2008)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nozaki, M2
Li, Y2
Zhu, J1
Ambrosio, F1
Uehara, K2
Fu, FH2
Huard, J2
Ota, S1
Terada, S1
Gharaibeh, B1

Other Studies

2 other studies available for suramin and Bruise

ArticleYear
Improved muscle healing after contusion injury by the inhibitory effect of suramin on myostatin, a negative regulator of muscle growth.
    The American journal of sports medicine, 2008, Volume: 36, Issue:12

    Topics: Animals; Antineoplastic Agents; Cell Differentiation; Cell Line; Contusions; Down-Regulation; Fibros

2008
Timing of the administration of suramin treatment after muscle injury.
    Muscle & nerve, 2012, Volume: 46, Issue:1

    Topics: Animals; Antineoplastic Agents; Contusions; Drug Administration Schedule; Fibroblasts; Fibrosis; Fol

2012