Page last updated: 2024-11-04

suramin and Bacterial Infections

suramin has been researched along with Bacterial Infections in 2 studies

Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.

Bacterial Infections: Infections by bacteria, general or unspecified.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sanner, BM1
Doberauer, C1
Tepel, M1
Zidek, W1
Toshkov, A1
Neychev, H1
Dimov, V1

Other Studies

2 other studies available for suramin and Bacterial Infections

ArticleYear
Fulminant disease simulating bacterial sepsis with disseminated intravascular coagulation after a trip to East Africa.
    Intensive care medicine, 2000, Volume: 26, Issue:5

    Topics: Africa, Eastern; Animals; Bacterial Infections; Diagnosis, Differential; Disseminated Intravascular

2000
Suramin increases the nonspecific antibacterial resistance through macrophage activation.
    Acta microbiologica Bulgarica, 1986, Volume: 19

    Topics: Animals; Bacterial Infections; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Immun

1986